Industry - Pharmaceutical Preparations

  1. All Sectors
  2. Manufacturing
  3. Chemicals
Latest data: 12/20/2024 10:22:22 PM
1 Month
Buy/Sell Ratio 0.11
9%
91%
Buy Sell
$40.74 M ($370.37) M
66 Insiders 129 Insiders
114 Transactions 183 Transactions
11/20/2024 to 12/20/2024
3 Month
Buy/Sell Ratio 0.21
17%
83%
Buy Sell
$149.46 M ($711.78) M
132 Insiders 278 Insiders
378 Transactions 483 Transactions
9/20/2024 to 12/20/2024
6 Month
Buy/Sell Ratio 0.27
21%
79%
Buy Sell
$271.49 M ($1,012.41) M
219 Insiders 469 Insiders
566 Transactions 1042 Transactions
6/20/2024 to 12/20/2024
12 Month
Buy/Sell Ratio 0.29
22%
78%
Buy Sell
$572.89 M ($1,966.95) M
368 Insiders 863 Insiders
1008 Transactions 2500 Transactions
12/20/2023 to 12/20/2024

Monthly Buy and Sell Value

Monthly Buy/Sell Ratio

Most Insider Buying

12 months
Name Value Transactions
Janux Therapeutics, Inc.
$53,700,000 1
Climb Bio, Inc.
$49,952,817 1
Astria Therapeutics, Inc.
$34,587,522 2
Nkarta, Inc.
$30,000,000 1
Dyne Therapeutics, Inc.
$29,999,988 1
Pepgen Inc.
$27,212,790 1
ALUMIS INC.
$25,000,000 1
Bicycle Therapeutics Plc
$21,230,385 2
89Bio, Inc.
$20,722,500 1
Precigen, Inc.
$20,136,327 2

Most Insider Selling

12 months
Name Value Transactions
Beigene, Ltd.
($194,200,043) 1
Nuvalent, Inc.
($174,035,959) 2
Regeneron Pharmaceuticals, Inc.
($127,756,672) 4
MoonLake Immunotherapeutics
($100,003,200) 1
Nuvalent, Inc.
($97,750,000) 1
Dyne Therapeutics, Inc.
($97,727,621) 43
Roivant Sciences Ltd.
($51,232,227) 5
Dyne Therapeutics, Inc.
($44,258,207) 11
Janux Therapeutics, Inc.
($37,081,025) 1
Abbvie Inc.
($36,976,038) 2

Most Unique Insiders Buying (>25K)

12 months
Name Unique insiders Total Trades
Opko Health, Inc. 5 25
Relmada Therapeutics, Inc. 5 16
Maia Biotechnology, Inc. 5 12
Biohaven Ltd. 4 12
CalciMedica, Inc. 4 9
Immunome Inc. 4 8
Elanco Animal Health Inc 4 6
Avadel Pharmaceuticals Plc 4 5
Perrigo Co Plc 4 4
Nuvation Bio Inc. 3 6

Most Unique Insiders Selling (>25K)

12 months
Name Unique insiders Total Trades
Vertex Pharmaceuticals Inc / Ma 12 51
Apellis Pharmaceuticals, Inc. 12 45
Blueprint Medicines Corp 12 22
Puma Biotechnology, Inc. 11 13
Xencor Inc 11 13
Ani Pharmaceuticals Inc 10 46
Arrowhead Pharmaceuticals, Inc. 10 20
Ionis Pharmaceuticals Inc 10 18
Aurinia Pharmaceuticals Inc. 10 13
Ultragenyx Pharmaceutical Inc. 9 15

Companies with activity

1 Month 6 Month 12 Month
Name Ratio Buy $ Sell $ Ratio Buy $ Sell $ Ratio Buy $ Sell $
TALPHERA, INC. 57.61 $6,849 ($119) 121.52 $14,447 ($119) 204.43 $24,303 ($119)
Phathom Pharmaceuticals, Inc. 9.36 $180,332 ($19,272) 0.30 $180,332 ($594,419) 0.22 $180,332 ($834,960)
Arcutis Biotherapeutics, Inc. 0.27 $34,024 ($125,133) 0.03 $34,024 ($1,280,213) 0.12 $247,554 ($1,983,561)
Beigene, Ltd. 0.00 $0 ($194,200,043) 0.00 $0 ($202,613,222) 0.00 $0 ($219,815,720)
Nuvalent, Inc. 0.00 $0 ($110,192,443) 0.00 $0 ($212,957,419) 0.00 $0 ($307,164,357)
Dyne Therapeutics, Inc. 0.00 $0 ($11,446,931) 0.00 $264,304 ($99,340,406) 0.21 $30,264,292 ($146,012,573)
Olema Pharmaceuticals, Inc. 0.00 $0 ($11,396,670) 0.00 $0 ($11,751,242) 0.00 $0 ($30,902,451)
Verona Pharma Plc 0.00 $0 ($11,164,654) 0.02 $579,386 ($25,269,002) 0.02 $579,386 ($25,420,537)
Checkpoint Therapeutics, Inc. 0.00 $0 ($4,151,176) 0.00 $0 ($4,228,485) 0.00 $0 ($4,276,782)
ARS Pharmaceuticals, Inc. 0.00 $0 ($3,895,422) 0.00 $0 ($41,773,210) 0.27 $13,289,410 ($48,683,777)
Alnylam Pharmaceuticals, Inc. 0.00 $0 ($3,717,534) 0.00 $0 ($8,990,280) 0.00 $0 ($10,523,327)
Madrigal Pharmaceuticals, Inc. 0.00 $0 ($2,544,191) 0.00 $0 ($4,095,681) 0.00 $0 ($4,335,349)
Janux Therapeutics, Inc. 0.00 $0 ($2,294,879) 10.69 $53,700,000 ($5,022,795) 1.09 $53,700,000 ($49,286,802)
Avidity Biosciences, Inc. 0.00 $0 ($2,184,921) 0.00 $0 ($5,815,555) 0.00 $0 ($12,790,509)
Organogenesis Holdings Inc. 0.00 $0 ($1,146,424) 0.00 $0 ($1,146,424) 0.00 $0 ($1,146,424)
Arrowhead Pharmaceuticals, Inc. 0.00 $0 ($1,050,765) 0.00 $0 ($1,288,246) 0.01 $82,990 ($6,071,231)
Atea Pharmaceuticals, Inc. 0.00 $0 ($1,023,475) 0.00 $0 ($1,257,630) 0.00 $0 ($1,322,798)
Centessa Pharmaceuticals Plc 0.00 $0 ($959,057) 0.00 $0 ($4,216,795) 0.00 $0 ($4,251,369)
Alkermes Plc. 0.00 $0 ($883,825) 0.00 $0 ($1,192,994) 0.00 $0 ($1,485,733)
Akero Therapeutics, Inc. 0.00 $0 ($871,099) 0.00 $0 ($1,645,067) 0.00 $0 ($2,527,440)
Stoke Therapeutics, Inc. 0.00 $0 ($688,642) 0.00 $0 ($721,421) 0.00 $0 ($1,547,961)
Blueprint Medicines Corp 0.00 $0 ($661,660) 0.00 $0 ($1,406,028) 0.00 $0 ($8,390,561)
Crinetics Pharmaceuticals, Inc. 0.00 $0 ($604,017) 0.00 $0 ($1,444,406) 0.00 $0 ($2,497,028)
Perrigo Co Plc 0.00 $0 ($497,495) 0.00 $0 ($2,092,745) 0.23 $485,895 ($2,092,745)
Ani Pharmaceuticals Inc 0.00 $0 ($492,485) 0.00 $0 ($6,570,968) 0.00 $0 ($34,087,641)
Amneal Pharmaceuticals, Inc. 0.00 $0 ($448,860) 0.00 $0 ($2,091,129) 0.00 $0 ($2,347,235)
Ultragenyx Pharmaceutical Inc. 0.00 $0 ($413,650) 0.00 $0 ($2,956,949) 0.00 $0 ($8,294,344)
Day One Biopharmaceuticals, Inc. 0.00 $0 ($399,339) 0.00 $0 ($1,922,637) 0.00 $0 ($6,061,564)
Entrada Therapeutics, Inc. 0.00 $0 ($320,620) 0.00 $0 ($980,605) 0.45 $641,939 ($1,433,376)
Savara Inc 0.00 $0 ($290,675) 1.19 $346,672 ($290,675) 0.47 $346,672 ($733,706)
Ocular Therapeutix, Inc 0.00 $0 ($255,316) 0.00 $0 ($460,178) 0.00 $0 ($604,497)
Jazz Pharmaceuticals Plc 0.00 $0 ($248,832) 0.00 $0 ($968,992) 0.73 $1,435,800 ($1,973,429)
Rocket Pharmaceuticals, Inc. 0.00 $0 ($235,990) 0.00 $0 ($673,912) 0.00 $0 ($10,046,452)
Corcept Therapeutics Inc 0.00 $0 ($226,658) 0.00 $0 ($337,394) 0.00 $0 ($337,394)
Sarepta Therapeutics, Inc. 0.00 $0 ($205,400) 4.82 $4,955,728 ($1,027,499) 1.85 $4,955,728 ($2,677,745)
Nektar Therapeutics 0.00 $0 ($179,698) 0.00 $0 ($245,542) 0.00 $0 ($346,830)
Apellis Pharmaceuticals, Inc. 0.00 $0 ($171,175) 0.00 $0 ($2,992,278) 0.00 $0 ($12,071,619)
Ardelyx, Inc. 0.00 $0 ($134,482) 0.61 $996,598 ($1,630,309) 0.23 $996,598 ($4,418,841)
Enanta Pharmaceuticals Inc 0.00 $0 ($126,993) 0.00 $0 ($126,993) 0.00 $0 ($216,583)
Tyra Biosciences, Inc. 0.00 $0 ($79,242) 2.72 $19,988,021 ($7,350,731) 2.06 $19,988,021 ($9,681,727)
GENELUX CORP 0.00 $0 ($59,034) 0.00 $0 ($95,722) 0.00 $0 ($95,722)
Syros Pharmaceuticals, Inc. 0.00 $0 ($45,756) 1.07 $321,920 ($300,686) 12.26 $4,321,918 ($352,418)
GYRE THERAPEUTICS, INC. 0.00 $0 ($44,852) 0.00 $0 ($44,852) 0.00 $0 ($44,852)
Esperion Therapeutics, Inc. 0.00 $0 ($43,987) 0.00 $0 ($78,495) 0.00 $0 ($95,644)
Uniqure N.V. 0.00 $0 ($39,639) 0.00 $0 ($45,948) 0.00 $0 ($529,348)
Igm Biosciences, Inc. 0.00 $0 ($37,535) 0.00 $0 ($167,785) 6.39 $3,425,569 ($536,159)
Amylyx Pharmaceuticals, Inc. 0.00 $0 ($30,007) 2.01 $427,758 ($213,250) 0.56 $437,194 ($784,423)
Design Therapeutics, Inc. 0.00 $0 ($23,864) 0.00 $0 ($3,487,078) 0.03 $104,604 ($3,487,078)
Cryoport, Inc. 0.00 $0 ($16,200) 0.00 $0 ($43,060) 0.00 $0 ($286,858)
Contineum Therapeutics, Inc. 0.00 $0 ($16,177) 0.00 $0 ($117,598) 0.00 $0 ($117,598)
Cassava Sciences Inc 0.00 $0 ($15,480) 0.00 $0 ($15,480) 0.00 $0 ($15,480)
Pacira Biosciences, Inc. 0.00 $0 ($9,880) 1.87 $215,684 ($115,374) 0.05 $215,684 ($4,293,654)
Mural Oncology plc 0.00 $0 ($9,394) 0.34 $32,071 ($95,400) 0.34 $32,071 ($95,400)
Verastem, Inc. 0.00 $0 ($7,930) 0.00 $0 ($23,427) 0.00 $0 ($275,205)
2Seventy Bio, Inc. 0.00 $0 ($7,393) 0.00 $0 ($63,367) 6.91 $4,103,042 ($594,035)
Bausch Health Companies Inc. 0.00 $0 ($3,674) 0.00 $0 ($86,702) 0.00 $0 ($148,569)
Optinose, Inc. 0.00 $0 ($3,372) 0.00 $0 ($201,579) 0.00 $0 ($370,388)
Arcus Biosciences, Inc. 0.00 $0 ($3,079) 0.00 $0 ($23,394) 0.00 $0 ($2,750,629)
Karyopharm Therapeutics Inc. 0.00 $0 ($2,932) 0.00 $0 ($33,406) 0.00 $0 ($2,017,098)
Longeveron Inc. 0.00 $0 ($2,588) 0.00 $0 ($2,588) 283.72 $734,300 ($2,588)
Oragenics Inc 0.00 $0 ($1,319) 0.00 $0 ($1,319) 0.00 $0 ($1,319)
Aquestive Therapeutics, Inc. 0.00 $0 ($214) 0.00 $0 ($214) 0.00 $0 ($300,214)
Avenue Therapeutics, Inc. 0.00 $0 ($46) 6.84 $1,250 ($183) 6.84 $1,250 ($183)
Bicycle Therapeutics Plc -- $21,230,385 $0 73.70 $21,230,385 ($288,057) 26.29 $21,230,385 ($807,503)
Aurinia Pharmaceuticals Inc. -- $10,822,000 $0 111.68 $10,822,000 ($96,902) 5.33 $10,822,000 ($2,030,788)
Neurogene Inc. -- $1,460,400 $0 -- $1,460,400 $0 -- $1,460,400 $0
Opko Health, Inc. -- $1,444,801 $0 -- $2,028,317 $0 -- $11,847,808 $0
Immunome Inc. -- $1,310,011 $0 -- $1,407,619 $0 -- $2,822,831 $0
Ventyx Biosciences, Inc. -- $959,889 $0 -- $959,889 $0 19.70 $959,889 ($48,734)
Zenas Biopharma, Inc. -- $718,100 $0 -- $2,227,836 $0 -- $2,227,836 $0
Avadel Pharmaceuticals Plc -- $406,367 $0 -- $406,367 $0 0.40 $435,367 ($1,089,750)
Benitec Biopharma Inc. -- $403,200 $0 -- $819,816 $0 -- $819,816 $0
89Bio, Inc. -- $202,950 $0 0.89 $202,950 ($226,995) 76.05 $20,925,450 ($275,167)
An2 Therapeutics, Inc. -- $195,193 $0 -- $483,337 $0 0.13 $483,337 ($3,731,312)
Johnson & Johnson -- $147,220 $0 -- $147,220 $0 0.10 $147,220 ($1,441,765)
Maia Biotechnology, Inc. -- $146,798 $0 -- $731,126 $0 -- $1,600,150 $0
Forte Biosciences, Inc. -- $124,998 $0 -- $124,998 $0 -- $124,998 $0
Prelude Therapeutics Inc -- $121,963 $0 -- $121,963 $0 -- $121,963 $0
Lexaria Bioscience Corp. -- $118,392 $0 12.02 $123,400 ($10,268) 12.02 $123,400 ($10,268)
60 DEGREES PHARMACEUTICALS, INC. -- $114,350 $0 -- $126,023 $0 -- $135,763 $0
Terns Pharmaceuticals, Inc. -- $110,468 $0 4.13 $5,110,462 ($1,236,860) 4.17 $5,153,007 ($1,236,860)
Rezolute, Inc. -- $84,300 $0 -- $124,300 $0 -- $658,497 $0
Pieris Pharmaceuticals, Inc. -- $51,720 $0 -- $51,720 $0 -- $51,720 $0
Rani Therapeutics Holdings, Inc. -- $49,967 $0 -- $49,967 $0 -- $49,967 $0
Nrx Pharmaceuticals, Inc. -- $46,800 $0 -- $46,800 $0 -- $46,800 $0
Alx Oncology Holdings Inc -- $46,404 $0 0.42 $46,404 ($109,632) 0.26 $198,514 ($768,982)
Cue Biopharma, Inc. -- $30,900 $0 -- $30,900 $0 -- $30,900 $0
Earth Science Tech, Inc. -- $27,450 $0 -- $186,611 $0 -- $406,046 $0
Serina Therapeutics, Inc. -- $17,745 $0 -- $441,627 $0 -- $730,976 $0
Annexon, Inc. -- $17,056 $0 0.61 $89,664 ($147,610) 4.65 $1,147,517 ($246,530)
Greenwich Lifesciences, Inc. -- $12,910 $0 -- $201,030 $0 -- $3,192,992 $0
CalciMedica, Inc. -- $12,720 $0 -- $1,344,745 $0 -- $2,261,249 $0
Pyxis Oncology, Inc. -- $10,900 $0 -- $10,900 $0 -- $10,900 $0
BIOADAPTIVES, INC. -- $10,625 $0 -- $10,625 $0 -- $10,625 $0
Opus Genetics, Inc. -- $9,834 $0 -- $110,992 $0 -- $200,092 $0
Tharimmune, Inc. -- $9,752 $0 -- $34,719 $0 -- $34,719 $0
ALT5 Sigma Corp -- $9,000 $0 -- $19,278 $0 -- $19,278 $0
Oncotelic Therapeutics, Inc. -- $8,627 $0 -- $18,627 $0 -- $18,627 $0
IMPACT BIOMEDICAL INC. -- $5,173 $0 -- $5,173 $0 -- $5,173 $0
Cumberland Pharmaceuticals Inc -- $4,371 $0 -- $27,287 $0 -- $27,287 $0
Silo Pharma, Inc. -- $4,347 $0 -- $6,722 $0 -- $22,955 $0
Kairos Pharma, LTD. -- $4,068 $0 -- $9,828 $0 -- $9,828 $0
Lifevantage Corp -- $3,632 $0 -- $14,004 $0 -- $21,884 $0
Aileron Therapeutics, Inc. -- $898 $0 -- $898 $0 -- $898 $0
Shattuck Labs, Inc. -- $0 $0 -- $126,999 $0 0.51 $126,999 ($250,000)
Enliven Therapeutics, Inc. -- $0 $0 0.00 $0 ($6,502,853) 0.00 $0 ($53,080,897)
Bridgebio Pharma, Inc. -- $0 $0 0.00 $0 ($706,963) 0.00 $0 ($5,073,755)
Eli Lilly & Co -- $0 $0 0.00 $0 ($1,435,542) 0.00 $0 ($8,396,890)
Emmaus Life Sciences, Inc. -- $0 $0 -- $800 $0 -- $15,494 $0
Arvinas, Inc. -- $0 $0 0.00 $0 ($6,396) 0.00 $0 ($490,917)
Amphastar Pharmaceuticals, Inc. -- $0 $0 0.00 $0 ($286,586) 0.00 $0 ($21,114,942)
Nurix Therapeutics, Inc. -- $0 $0 0.00 $0 ($665,029) 0.00 $0 ($1,178,346)
Precigen, Inc. -- $0 $0 -- $20,049,999 $0 148.07 $20,186,326 ($136,327)
Puma Biotechnology, Inc. -- $0 $0 0.00 $0 ($314,077) 0.00 $0 ($1,024,236)
G1 Therapeutics, Inc. -- $0 $0 0.00 $0 ($42,917) 0.00 $0 ($651,074)
KALA BIO, Inc. -- $0 $0 0.00 $0 ($164,497) 0.00 $0 ($314,044)
Zentalis Pharmaceuticals, Inc. -- $0 $0 0.00 $0 ($5,098) 0.00 $0 ($495,115)
Harmony Biosciences Holdings, Inc. -- $0 $0 0.00 $0 ($1,274,547) 0.00 $0 ($1,274,547)
Kezar Life Sciences, Inc. -- $0 $0 0.00 $0 ($3,879) 0.00 $0 ($3,879)
Y-Mabs Therapeutics, Inc. -- $0 $0 0.00 $0 ($1,338,100) 0.00 $0 ($2,703,613)
Regeneron Pharmaceuticals, Inc. -- $0 $0 0.00 $0 ($9,544,884) 0.00 $0 ($193,916,453)
Arcturus Therapeutics Holdings Inc. -- $0 $0 0.00 $0 ($249,121) 0.00 $0 ($3,806,398)
Travere Therapeutics, Inc. -- $0 $0 0.00 $0 ($437,368) 0.00 $0 ($959,389)
Ptc Therapeutics, Inc. -- $0 $0 0.00 $0 ($77,200) 0.00 $0 ($1,256,640)
United Therapeutics Corp -- $0 $0 0.00 $0 ($1,091,012) 0.00 $0 ($2,046,843)
Insmed Inc -- $0 $0 0.00 $0 ($686,408) 0.00 $0 ($4,410,444)
Anixa Biosciences Inc -- $0 $0 -- $125,278 $0 -- $441,280 $0
Cartesian Therapeutics, Inc. -- $0 $0 -- $11,864,290 $0 -- $12,553,352 $0
Keros Therapeutics, Inc. -- $0 $0 0.00 $0 ($22,005,000) 0.00 $0 ($22,005,000)
Tg Therapeutics, Inc. -- $0 $0 0.00 $0 ($1,396,675) 0.00 $0 ($3,403,035)
Acadia Pharmaceuticals Inc -- $0 $0 0.00 $0 ($779,494) 0.00 $0 ($1,285,849)
Tempest Therapeutics, Inc. -- $0 $0 -- $100,001 $0 -- $100,001 $0
Catalent, Inc. -- $0 $0 0.00 $0 ($1,474,140) 0.00 $0 ($1,571,912)
Galectin Therapeutics Inc -- $0 $0 -- $40,738 $0 -- $62,897 $0
Clearside Biomedical, Inc. -- $0 $0 -- $61,410 $0 6.33 $249,310 ($39,372)
Biomarin Pharmaceutical Inc -- $0 $0 0.00 $0 ($414,584) 0.00 $0 ($6,829,463)
LIFECORE BIOMEDICAL, INC. \DE\ -- $0 $0 -- $5,376,379 $0 -- $5,376,379 $0
Biomea Fusion, Inc. -- $0 $0 -- $100,600 $0 -- $155,961 $0
Zai Lab Ltd -- $0 $0 0.00 $0 ($279,298) 0.17 $126,690 ($727,751)
Regulus Therapeutics Inc. -- $0 $0 -- $7,280 $0 0.24 $7,280 ($30,379)
Vertex Pharmaceuticals Inc / Ma -- $0 $0 0.00 $0 ($31,358,112) 0.00 $0 ($82,560,514)
Mannkind Corp -- $0 $0 0.00 $0 ($1,700,719) 0.00 $0 ($1,960,064)
Clene Inc. -- $0 $0 -- $583,390 $0 -- $583,390 $0
Chimerix Inc -- $0 $0 0.00 $0 ($1,065) 0.00 $0 ($7,673)
Abbvie Inc. -- $0 $0 0.00 $0 ($12,403,580) 0.00 $0 ($43,806,582)
Nuvectis Pharma, Inc. -- $0 $0 4.82 $108,380 ($22,478) 8.71 $195,885 ($22,478)
Eyenovia, Inc. -- $0 $0 -- $42,577 $0 -- $42,577 $0
Cytokinetics Inc -- $0 $0 0.00 $0 ($635,391) 0.00 $0 ($4,416,547)
Teva Pharmaceutical Industries Ltd -- $0 $0 0.00 $0 ($2,494,418) 0.00 $0 ($14,713,449)
Aclaris Therapeutics, Inc. -- $0 $0 -- $1,499,998 $0 -- $1,517,954 $0
Vera Therapeutics, Inc. -- $0 $0 0.00 $0 ($1,992,151) 0.14 $4,999,990 ($36,320,294)
Agios Pharmaceuticals, Inc. -- $0 $0 0.00 $0 ($1,179,076) 0.00 $0 ($1,505,225)
Wave Life Sciences Ltd. -- $0 $0 0.00 $0 ($2,524,650) 0.00 $0 ($2,621,072)
Abbott Laboratories -- $0 $0 0.00 $0 ($3,100) 0.00 $0 ($2,959,611)
Xeris Biopharma Holdings, Inc. -- $0 $0 -- $20,281 $0 -- $40,315 $0
Vaccinex, Inc. -- $0 $0 -- $1,316,317 $0 585.22 $1,326,861 ($2,267)
Bristol Myers Squibb Co -- $0 $0 2.57 $100,055 ($38,930) 2.57 $100,055 ($38,930)
Collegium Pharmaceutical, Inc -- $0 $0 0.00 $0 ($1,125,111) 0.00 $0 ($3,775,029)
Aprea Therapeutics, Inc. -- $0 $0 5.61 $165,941 ($29,583) 9.73 $287,903 ($29,583)
Cara Therapeutics, Inc. -- $0 $0 0.00 $0 ($2,516) 0.00 $0 ($42,686)
Ligand Pharmaceuticals Inc -- $0 $0 0.06 $243,480 ($3,916,071) 0.04 $243,480 ($5,489,525)
Vanda Pharmaceuticals Inc. -- $0 $0 0.00 $0 ($39,190) 0.00 $0 ($552,533)
Theravance Biopharma, Inc. -- $0 $0 0.00 $0 ($72,000) 0.00 $0 ($82,922)
Ironwood Pharmaceuticals Inc -- $0 $0 0.00 $0 ($122,335) 0.03 $160,420 ($5,863,381)
Elanco Animal Health Inc -- $0 $0 -- $1,352,584 $0 -- $2,225,086 $0
Imunon, Inc. -- $0 $0 -- $50,250 $0 -- $50,250 $0
Xencor Inc -- $0 $0 0.00 $0 ($300,253) 0.00 $1,013 ($1,191,391)
Roivant Sciences Ltd. -- $0 $0 0.00 $0 ($57,098,536) 0.00 $0 ($57,098,536)
Evolus, Inc. -- $0 $0 0.00 $0 ($138,326) 0.00 $0 ($3,206,793)
Glycomimetics Inc -- $0 $0 -- $30,716 $0 -- $83,159 $0
Generation Bio Co. -- $0 $0 0.00 $0 ($18,410) 0.00 $0 ($26,332)
Spyre Therapeutics, Inc. -- $0 $0 0.00 $0 ($779,316) 0.00 $0 ($779,316)
Viatris Inc -- $0 $0 0.00 $0 ($7,399,468) 0.00 $0 ($15,092,620)
Cingulate Inc. -- $0 $0 0.00 $0 ($841) 0.00 $0 ($841)
Gossamer Bio, Inc. -- $0 $0 198.60 $250,282 ($1,260) 6.06 $324,442 ($53,578)
Protokinetix, Inc. -- $0 $0 -- $20,000 $0 -- $230,000 $0
Applied Therapeutics, Inc. -- $0 $0 0.00 $0 ($4,923,159) 0.00 $0 ($8,091,115)
Assembly Biosciences, Inc. -- $0 $0 0.00 $0 ($31,029) 0.00 $0 ($139,156)
Alzamend Neuro, Inc. -- $0 $0 -- $300 $0 -- $8,512 $0
Relmada Therapeutics, Inc. -- $0 $0 -- $642,845 $0 -- $1,306,220 $0
Ionis Pharmaceuticals Inc -- $0 $0 0.00 $0 ($957,797) 0.00 $0 ($5,405,937)
Lumos Pharma, Inc. -- $0 $0 0.00 $0 ($6,426) 0.00 $0 ($13,897)
Synlogic, Inc. -- $0 $0 0.00 $0 ($111) 0.00 $0 ($1,079)
Assertio Holdings, Inc. -- $0 $0 -- $69,950 $0 9.19 $105,300 ($11,463)
Nuvation Bio Inc. -- $0 $0 13.97 $2,275,466 ($162,883) 18.65 $3,037,822 ($162,883)
Disc Medicine, Inc. -- $0 $0 0.00 $0 ($147,000) 1.36 $14,000,076 ($10,283,664)
Liquidia Corp -- $0 $0 6.11 $2,999,994 ($490,915) 2.11 $2,999,994 ($1,424,400)
Schrodinger, Inc. -- $0 $0 0.00 $0 ($27,226) 0.00 $0 ($216,981)
Bespoke Extracts, Inc. -- $0 $0 -- $2,080 $0 -- $10,028 $0
KIORA PHARMACEUTICALS INC -- $0 $0 -- $46,445 $0 -- $95,206 $0
Avalo Therapeutics, Inc. -- $0 $0 -- $12,750 $0 -- $12,750 $0
Emergent Biosolutions Inc. -- $0 $0 0.00 $0 ($443,765) 0.00 $0 ($519,596)
Protagonist Therapeutics, Inc -- $0 $0 0.00 $0 ($78,108) 0.00 $0 ($2,997,094)
Bioxcel Therapeutics, Inc. -- $0 $0 0.00 $0 ($18,173) 0.00 $0 ($423,308)
Nkarta, Inc. -- $0 $0 0.00 $0 ($27,168) 144.55 $45,483,410 ($314,664)
Amarin Corp Plc\Uk -- $0 $0 -- $102,400 $0 -- $118,124 $0
Zomedica Corp. -- $0 $0 -- $142,640 $0 -- $376,238 $0
Phibro Animal Health Corp -- $0 $0 -- $100,100 $0 -- $100,100 $0
Anaptysbio, Inc -- $0 $0 0.00 $0 ($45,182) 0.00 $0 ($3,542,639)
Monopar Therapeutics -- $0 $0 -- $25,188 $0 -- $125,187 $0
Galera Therapeutics, Inc. -- $0 $0 0.00 $0 ($4,825) 0.00 $0 ($4,825)
Vtv Therapeutics Inc. -- $0 $0 -- $83,812 $0 -- $83,812 $0
Allakos Inc. -- $0 $0 0.00 $0 ($87,935) 0.00 $0 ($87,935)
Immunic, Inc. -- $0 $0 -- $100,369 $0 -- $118,702 $0
Essa Pharma Inc. -- $0 $0 0.00 $0 ($20,903) 0.00 $0 ($41,740)
Prestige Consumer Healthcare Inc. -- $0 $0 0.00 $0 ($1,545,852) 0.00 $0 ($1,545,852)
IGC Pharma, Inc. -- $0 $0 -- $200,000 $0 -- $200,000 $0
Mirum Pharmaceuticals, Inc. -- $0 $0 -- $13,864 $0 0.18 $115,064 ($622,919)
MARINUS PHARMACEUTICALS, INC. -- $0 $0 0.00 $0 ($32,888) 0.00 $0 ($248,297)
Kura Oncology, Inc. -- $0 $0 0.00 $0 ($8,434) 0.00 $0 ($402,181)
Pliant Therapeutics, Inc. -- $0 $0 0.00 $0 ($918,974) 0.00 $0 ($1,966,213)
Edgewise Therapeutics, Inc. -- $0 $0 0.00 $0 ($202,603) 5.31 $10,100,948 ($1,901,919)
Pmv Pharmaceuticals, Inc. -- $0 $0 0.00 $0 ($15,200) 0.00 $0 ($15,200)
Fortress Biotech, Inc. -- $0 $0 -- $1,437,305 $0 83.26 $1,573,664 ($18,900)
Supernus Pharmaceuticals, Inc. -- $0 $0 0.00 $0 ($316,434) 0.00 $0 ($316,434)
Pfizer Inc -- $0 $0 0.19 $28,240 ($147,714) 0.19 $28,240 ($147,714)
Therapeuticsmd, Inc. -- $0 $0 -- $9,138 $0 -- $9,138 $0
ZEVRA THERAPEUTICS, INC. -- $0 $0 -- $144,224 $0 -- $144,224 $0
CervoMed Inc. -- $0 $0 -- $18,160 $0 -- $18,160 $0
Cormedix Inc. -- $0 $0 -- $14,985 $0 -- $65,703 $0
Kronos Bio, Inc. -- $0 $0 -- $733,801 $0 56.02 $3,852,882 ($68,776)
Verrica Pharmaceuticals Inc. -- $0 $0 0.00 $0 ($1,077,201) 0.00 $0 ($1,077,201)
Equillium, Inc. -- $0 $0 0.00 $0 ($79,933) 0.00 $0 ($79,933)
Viking Therapeutics, Inc. -- $0 $0 0.00 $0 ($8,622,728) 0.00 $0 ($10,236,728)
Palatin Technologies Inc -- $0 $0 0.00 $0 ($8,274) 0.40 $12,703 ($31,707)
Aridis Pharmaceuticals, Inc. -- $0 $0 -- $100,000 $0 -- $100,000 $0
Climb Bio, Inc. -- $0 $0 16.07 $49,952,817 ($3,108,685) 16.07 $49,952,817 ($3,108,685)
Catalyst Pharmaceuticals, Inc. -- $0 $0 0.00 $0 ($3,052,900) 0.00 $0 ($3,672,033)
Revance Therapeutics, Inc. -- $0 $0 0.00 $0 ($16,296) 1.31 $209,400 ($160,014)
Immix Biopharma, Inc. -- $0 $0 -- $89,740 $0 -- $132,220 $0
Spero Therapeutics, Inc. -- $0 $0 0.00 $0 ($110,345) 0.00 $0 ($428,388)
Aldeyra Therapeutics, Inc. -- $0 $0 0.00 $0 ($127,288) 0.00 $0 ($888,124)
Rockwell Medical, Inc. -- $0 $0 0.00 $0 ($82,039) 0.00 $0 ($82,039)
Hoth Therapeutics, Inc. -- $0 $0 -- $16,750 $0 -- $16,750 $0
Unity Biotechnology, Inc. -- $0 $0 0.00 $0 ($4,560) 0.00 $0 ($8,680)
Skye Bioscience, Inc. -- $0 $0 0.00 $0 ($2,647,684) 0.00 $0 ($2,647,684)
Tango Therapeutics, Inc. -- $0 $0 -- $74,000 $0 0.28 $74,000 ($266,259)
Geovax Labs, Inc. -- $0 $0 -- $15,600 $0 -- $43,421 $0
MoonLake Immunotherapeutics -- $0 $0 0.00 $0 ($109,189,320) 0.00 $0 ($131,013,871)
Foghorn Therapeutics Inc. -- $0 $0 0.00 $0 ($190,000) 0.00 $0 ($262,134)
Maravai Lifesciences Holdings, Inc. -- $0 $0 -- $1,087,625 $0 -- $1,087,625 $0
Scynexis Inc -- $0 $0 -- $27,400 $0 -- $27,400 $0
Gain Therapeutics, Inc. -- $0 $0 -- $85,154 $0 -- $200,924 $0
Promis Neurosciences Inc. -- $0 $0 -- $268,242 $0 -- $268,242 $0
Aadi Bioscience, Inc. -- $0 $0 0.00 $0 ($182,887) 0.00 $0 ($666,656)
Biohaven Ltd. -- $0 $0 -- $3,233,889 $0 -- $15,752,137 $0
Journey Medical Corp -- $0 $0 0.00 $0 ($72,899) 2.89 $237,290 ($82,087)
CONDUIT PHARMACEUTICALS INC. -- $0 $0 0.00 $0 ($4,592,487) 0.00 $0 ($4,592,487)
Mereo Biopharma Group plc -- $0 $0 0.00 $0 ($2,315,682) 0.00 $0 ($2,315,682)
Flora Growth Corp. -- $0 $0 -- $30,759 $0 -- $1,030,757 $0
ELITE PHARMACEUTICALS INC /NV/ -- $0 $0 0.00 $0 ($562,305) 0.00 $0 ($562,305)
Quoin Pharmaceuticals, Ltd. -- $0 $0 -- $80,858 $0 371.93 $80,858 ($217)
Entero Therapeutics, Inc. -- $0 $0 0.00 $0 ($2,256) 0.00 $0 ($19,333)
NewAmsterdam Pharma Co N.V. -- $0 $0 -- $98,683 $0 -- $461,215 $0
BullFrog AI Holdings, Inc. -- $0 $0 0.00 $0 ($213,201) 0.00 $0 ($686,219)
Mineralys Therapeutics, Inc. -- $0 $0 0.00 $0 ($7,881,407) 0.00 $0 ($10,650,350)
Coya Therapeutics, Inc. -- $0 $0 -- $106,393 $0 -- $106,393 $0
Bio Essence Corp -- $0 $0 0.00 $0 ($2,492,803) 0.00 $0 ($2,492,803)
ACELYRIN, Inc. -- $0 $0 0.00 $0 ($7) 0.00 $0 ($264,623)
Sagimet Biosciences Inc. -- $0 $0 0.00 $0 ($178,175) 0.36 $63,731 ($178,175)
MIRA PHARMACEUTICALS, INC. -- $0 $0 0.00 $0 ($133,649) 0.06 $8,176 ($133,649)
FibroBiologics, Inc. -- $0 $0 -- $35,269 $0 -- $35,269 $0
Alto Neuroscience, Inc. -- $0 $0 -- $190,833 $0 -- $316,469 $0
Rapport Therapeutics, Inc. -- $0 $0 -- $348,303 $0 -- $348,303 $0
ALUMIS INC. -- $0 $0 -- $25,000,000 $0 -- $25,000,000 $0
ACTUATE THERAPEUTICS, INC. -- $0 $0 0.00 $0 ($85,024) 0.00 $0 ($85,024)
Bioage Labs, Inc. -- $0 $0 -- $4,329,019 $0 -- $4,329,019 $0
Clever Leaves Holdings Inc. -- $0 $0 -- $0 $0 0.00 $0 ($7,066)
Alpine Immune Sciences, Inc. -- $0 $0 -- $0 $0 0.00 $0 ($57,343,468)
Amicus Therapeutics, Inc. -- $0 $0 -- $0 $0 0.00 $0 ($3,816,060)
Processa Pharmaceuticals, Inc. -- $0 $0 -- $0 $0 -- $160,099 $0
Merrimack Pharmaceuticals Inc -- $0 $0 -- $0 $0 -- $651,754 $0
Akebia Therapeutics, Inc. -- $0 $0 -- $0 $0 0.00 $0 ($383,681)
Avid Bioservices, Inc. -- $0 $0 -- $0 $0 0.00 $0 ($137,461)
Mirati Therapeutics, Inc. -- $0 $0 -- $0 $0 0.00 $0 ($401,691)
Rapt Therapeutics, Inc. -- $0 $0 -- $0 $0 0.00 $0 ($74,656)
Inmed Pharmaceuticals Inc. -- $0 $0 -- $0 $0 -- $29,547 $0
Verve Therapeutics, Inc. -- $0 $0 -- $0 $0 -- $475,760 $0
Urogen Pharma Ltd. -- $0 $0 -- $0 $0 0.00 $0 ($307,180)
Intra-Cellular Therapies, Inc. -- $0 $0 -- $0 $0 0.00 $0 ($5,016,172)
Q32 Bio Inc. -- $0 $0 -- $0 $0 0.00 $0 ($13,399)
Repare Therapeutics Inc. -- $0 $0 -- $0 $0 0.00 $0 ($101,063)
Xenon Pharmaceuticals Inc. -- $0 $0 -- $0 $0 0.00 $0 ($601,615)
Reshape Lifesciences Inc. -- $0 $0 -- $0 $0 0.00 $0 ($30)
Oncternal Therapeutics, Inc. -- $0 $0 -- $0 $0 10.74 $95,116 ($8,859)
Syndax Pharmaceuticals Inc -- $0 $0 -- $0 $0 -- $25,037 $0
Rhythm Pharmaceuticals, Inc. -- $0 $0 -- $0 $0 0.00 $0 ($6,436,104)
Zoetis Inc. -- $0 $0 -- $0 $0 0.00 $0 ($1,503,303)
Deciphera Pharmaceuticals, Inc. -- $0 $0 -- $0 $0 0.00 $0 ($276,125)
Dynavax Technologies Corp -- $0 $0 -- $0 $0 0.00 $0 ($43,127)
Edesa Biotech, Inc. -- $0 $0 -- $0 $0 -- $20,000 $0
Kalvista Pharmaceuticals, Inc. -- $0 $0 -- $0 $0 0.00 $0 ($3,554,042)
Immuneering Corp -- $0 $0 -- $0 $0 -- $477,955 $0
Iterum Therapeutics Plc -- $0 $0 -- $0 $0 -- $35,000 $0
Oric Pharmaceuticals, Inc. -- $0 $0 -- $0 $0 0.00 $0 ($1,137,726)
Royalty Pharma Plc -- $0 $0 -- $0 $0 0.00 $0 ($13,222,862)
Compass Pathways Plc -- $0 $0 -- $0 $0 0.00 $0 ($7,627,252)
Adicet Bio, Inc. -- $0 $0 -- $0 $0 1777.88 $15,000,000 ($8,437)
Fulcrum Therapeutics, Inc. -- $0 $0 -- $0 $0 8.33 $492,028 ($59,050)
Abeona Therapeutics Inc. -- $0 $0 -- $0 $0 0.90 $241,836 ($269,416)
Atreca, Inc. -- $0 $0 -- $0 $0 0.00 $0 ($1,455)
Fibrogen Inc -- $0 $0 -- $0 $0 -- $121,354 $0
Ideaya Biosciences, Inc. -- $0 $0 -- $0 $0 0.00 $0 ($252,120)
Kiniksa Pharmaceuticals International, plc -- $0 $0 -- $0 $0 0.00 $0 ($1,757,608)
Arbutus Biopharma Corp -- $0 $0 -- $0 $0 0.00 $0 ($78,849)
Elicio Therapeutics, Inc. -- $0 $0 -- $0 $0 -- $7,047,530 $0
Phio Pharmaceuticals Corp. -- $0 $0 -- $0 $0 -- $3,765 $0
Evofem Biosciences, Inc. -- $0 $0 -- $0 $0 0.00 $0 ($10)
Macrogenics Inc -- $0 $0 -- $0 $0 0.00 $0 ($1,312,199)
Veru Inc. -- $0 $0 -- $0 $0 0.06 $21,696 ($334,454)
Cytomx Therapeutics, Inc. -- $0 $0 -- $0 $0 0.00 $0 ($99,727)
Corvus Pharmaceuticals, Inc. -- $0 $0 -- $0 $0 -- $1,034,624 $0
Merck & Co., Inc. -- $0 $0 -- $0 $0 0.00 $0 ($309,996)
Summit Therapeutics Inc. -- $0 $0 -- $0 $0 -- $711,894 $0
Atai Life Sciences N.V. -- $0 $0 -- $0 $0 0.00 $0 ($521,476)
Larimar Therapeutics, Inc. -- $0 $0 -- $0 $0 -- $13,021,998 $0
Aerovate Therapeutics, Inc. -- $0 $0 -- $0 $0 4.12 $1,549,944 ($376,109)
Atossa Therapeutics, Inc. -- $0 $0 -- $0 $0 -- $44,250 $0
Ovid Therapeutics Inc. -- $0 $0 -- $0 $0 -- $50,364 $0
Erasca, Inc. -- $0 $0 -- $0 $0 -- $181,920 $0
Organon & Co. -- $0 $0 -- $0 $0 -- $49,939 $0
Cyclacel Pharmaceuticals, Inc. -- $0 $0 -- $0 $0 -- $26,374 $0
Axsome Therapeutics, Inc. -- $0 $0 -- $0 $0 0.00 $0 ($789,107)
Cns Pharmaceuticals, Inc. -- $0 $0 -- $0 $0 -- $89,999 $0
Astria Therapeutics, Inc. -- $0 $0 -- $0 $0 -- $34,587,522 $0
Natures Sunshine Products Inc -- $0 $0 -- $0 $0 0.00 $0 ($46,940)
Rigel Pharmaceuticals Inc -- $0 $0 -- $0 $0 0.00 $0 ($90,916)
HARROW, INC. -- $0 $0 -- $0 $0 -- $104,310 $0
Lianbio -- $0 $0 -- $0 $0 0.00 $0 ($7,513)
Pepgen Inc. -- $0 $0 -- $0 $0 202.93 $27,212,790 ($134,100)
Paxmedica, Inc. -- $0 $0 -- $0 $0 0.00 $0 ($615)
Third Harmonic Bio, Inc. -- $0 $0 -- $0 $0 0.00 $0 ($352,654)
ADC Therapeutics SA -- $0 $0 -- $0 $0 0.00 $0 ($225,811)
BriaCell Therapeutics Corp. -- $0 $0 -- $0 $0 -- $2,000,001 $0
Moleculin Biotech, Inc. -- $0 $0 -- $0 $0 -- $159,999 $0
LIPELLA PHARMACEUTICALS INC. -- $0 $0 -- $0 $0 -- $53,042 $0
Azitra, Inc. -- $0 $0 -- $0 $0 -- $115,514 $0