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Industry - Pharmaceutical Preparations
Officers
Directors
Officer & Directors
10 Percent
All
All Sectors
Manufacturing
Chemicals
Include option trades
Include indirect trades
Latest data: 12/3/2025 10:04:24 PM
1 Month
Buy/Sell Ratio 0.18
15%
85%
Buy
Sell
$14.56 M
($79.88) M
49 Insiders
125 Insiders
86 Transactions
147 Transactions
11/3/2025 to 12/3/2025
3 Month
Buy/Sell Ratio 0.19
15%
85%
Buy
Sell
$27.77 M
($146.52) M
90 Insiders
239 Insiders
144 Transactions
364 Transactions
9/3/2025 to 12/3/2025
6 Month
Buy/Sell Ratio 0.15
12%
88%
Buy
Sell
$46.58 M
($318.91) M
186 Insiders
425 Insiders
536 Transactions
850 Transactions
6/3/2025 to 12/3/2025
12 Month
Buy/Sell Ratio 0.13
11%
89%
Buy
Sell
$80.60 M
($614.09) M
357 Insiders
750 Insiders
1208 Transactions
1982 Transactions
12/3/2024 to 12/3/2025
Monthly Buy and Sell Value
Monthly Buy/Sell Ratio
Most Insider Buying
12 months
Name
Value
Transactions
Duggan Robert W
Summit Therapeutics Inc.
$5,984,756
2
Manning Paul B
Verrica Pharmaceuticals Inc.
$5,835,050
1
Mott David M
Ardelyx, Inc.
$5,781,187
7
Kewalramani Reshma
Vertex Pharmaceuticals Inc / Ma
$3,895,768
1
Bailey Gregory
Biohaven Ltd.
$3,000,000
1
Springer Timothy A
Cartesian Therapeutics, Inc.
$2,930,893
11
Wong Hing C
Hcw Biologics Inc.
$2,465,002
2
Hoffman Michael B
Annovis Bio, Inc.
$2,421,323
5
Siegall Clay B
Immunome Inc.
$2,161,959
2
Sachs Bruce I
Vertex Pharmaceuticals Inc / Ma
$1,948,416
1
Most Insider Selling
12 months
Name
Value
Transactions
Gonzalez Richard A
Abbvie Inc.
($20,263,020)
2
Oyler John
BeOne Medicines Ltd.
($19,580,110)
6
Lee Leo
Insmed Inc
($14,692,249)
1
Homcy Charles J
Bridgebio Pharma, Inc.
($13,912,443)
2
Jeffs Roger
Axsome Therapeutics, Inc.
($13,373,843)
6
Adsett Roger
Insmed Inc
($12,785,585)
12
Hahn Mark W
Verona Pharma Plc
($12,709,756)
7
Zaccardelli David
Verona Pharma Plc
($12,653,886)
7
Cheng Andrew
Akero Therapeutics, Inc.
($12,503,605)
11
Lian Brian
Viking Therapeutics, Inc.
($10,426,157)
3
Most Unique Insiders Buying (>25K)
12 months
Name
Unique insiders
Total Trades
Eli Lilly & Co
7
7
Hcw Biologics Inc.
6
8
Organon & Co.
6
6
Perrigo Co Plc
5
6
Quoin Pharmaceuticals, Ltd.
5
5
Relmada Therapeutics, Inc.
4
13
CervoMed Inc.
4
10
Avadel Pharmaceuticals Plc
4
5
Zomedica Corp.
4
5
Zentalis Pharmaceuticals, Inc.
4
4
Most Unique Insiders Selling (>25K)
12 months
Name
Unique insiders
Total Trades
Ani Pharmaceuticals Inc
12
27
Insmed Inc
11
66
Apellis Pharmaceuticals, Inc.
11
36
Ionis Pharmaceuticals Inc
11
24
Blueprint Medicines Corp
11
24
Puma Biotechnology, Inc.
11
14
Uniqure N.V.
10
16
Ptc Therapeutics, Inc.
9
37
Liquidia Corp
9
23
Arrowhead Pharmaceuticals, Inc.
9
22
Companies with activity
1 Month
6 Month
12 Month
Name
Ratio
Buy $
Sell $
Ratio
Buy $
Sell $
Ratio
Buy $
Sell $
Insmed Inc
0.00
$0
($17,673,849)
0.00
$0
($27,683,175)
0.00
$0
($67,607,256)
Mineralys Therapeutics, Inc.
0.00
$0
($9,088,499)
0.00
$0
($12,503,419)
0.00
$0
($13,257,626)
BeOne Medicines Ltd.
0.00
$0
($7,365,123)
0.00
$0
($30,934,765)
0.00
$0
($31,576,310)
Bridgebio Pharma, Inc.
0.00
$0
($5,554,221)
0.00
$0
($23,857,338)
0.00
$0
($23,896,847)
Jazz Pharmaceuticals Plc
0.00
$0
($5,458,839)
0.00
$0
($7,204,929)
0.00
$0
($11,003,601)
Tyra Biosciences, Inc.
0.00
$0
($4,138,990)
0.00
$0
($4,767,253)
0.00
$0
($4,767,253)
Arcutis Biotherapeutics, Inc.
0.00
$0
($2,766,335)
0.00
$0
($6,965,027)
0.00
$0
($9,578,496)
Liquidia Corp
0.00
$0
($2,671,829)
0.00
$0
($4,954,493)
0.00
$0
($6,417,989)
Stoke Therapeutics, Inc.
0.00
$0
($2,294,777)
0.00
$0
($5,612,677)
0.00
$0
($6,911,257)
Organogenesis Holdings Inc.
0.00
$0
($1,592,120)
0.46
$725,290
($1,592,120)
0.25
$725,290
($2,866,080)
Theravance Biopharma, Inc.
0.00
$0
($1,399,270)
0.00
$0
($1,513,140)
0.00
$0
($1,849,140)
Collegium Pharmaceutical, Inc
0.00
$0
($1,215,753)
0.00
$0
($1,887,330)
0.00
$0
($4,346,995)
Vertex Pharmaceuticals Inc / Ma
0.00
$0
($1,086,450)
3.98
$5,844,183
($1,469,831)
0.28
$5,844,183
($20,617,111)
Madrigal Pharmaceuticals, Inc.
0.00
$0
($1,082,986)
0.00
$0
($7,854,110)
0.00
$0
($11,287,540)
Teva Pharmaceutical Industries Ltd
0.00
$0
($1,053,885)
0.01
$20,988
($2,006,349)
0.00
$20,988
($10,990,218)
Eli Lilly & Co
0.00
$0
($1,010,500)
1.60
$4,036,828
($2,529,192)
0.43
$4,036,828
($9,316,457)
Royalty Pharma Plc
0.00
$0
($842,885)
0.00
$0
($842,885)
0.00
$0
($842,885)
Ani Pharmaceuticals Inc
0.00
$0
($785,812)
0.00
$0
($13,438,327)
0.00
$0
($14,591,064)
Acadia Pharmaceuticals Inc
0.00
$0
($670,983)
0.00
$0
($1,663,929)
0.00
$0
($1,893,602)
Nuvalent, Inc.
0.00
$0
($639,814)
0.00
$0
($5,331,876)
0.00
$0
($8,104,543)
Merck & Co., Inc.
0.00
$0
($616,395)
0.00
$0
($1,336,435)
0.57
$1,577,424
($2,772,787)
Ocular Therapeutix, Inc
0.00
$0
($613,453)
0.00
$0
($1,341,101)
0.03
$69,600
($1,999,856)
Ionis Pharmaceuticals Inc
0.00
$0
($609,379)
0.00
$0
($5,172,266)
0.09
$658,979
($7,345,565)
Amneal Pharmaceuticals, Inc.
0.00
$0
($586,000)
0.00
$0
($9,544,069)
0.00
$0
($16,539,804)
Amicus Therapeutics, Inc.
0.00
$0
($502,793)
0.00
$0
($502,793)
0.00
$0
($502,793)
Kura Oncology, Inc.
0.00
$0
($498,680)
0.60
$713,346
($1,196,690)
0.51
$713,346
($1,394,916)
Arrowhead Pharmaceuticals, Inc.
0.00
$0
($493,412)
0.00
$0
($2,218,412)
0.00
$0
($8,398,172)
Cytokinetics Inc
0.00
$0
($467,270)
0.00
$0
($4,362,241)
0.00
$0
($12,031,623)
Cytomx Therapeutics, Inc.
0.00
$0
($461,906)
0.00
$0
($461,906)
0.00
$0
($509,794)
Ardelyx, Inc.
0.00
$0
($452,741)
1.52
$1,463,140
($960,204)
3.83
$5,781,187
($1,511,019)
Spyre Therapeutics, Inc.
0.00
$0
($435,356)
0.00
$0
($1,784,773)
0.00
$0
($1,784,773)
Corcept Therapeutics Inc
0.00
$0
($364,070)
0.00
$0
($589,473)
0.00
$0
($2,344,021)
Natures Sunshine Products Inc
0.00
$0
($363,095)
0.00
$0
($772,898)
0.00
$0
($772,898)
Pacira Biosciences, Inc.
0.00
$0
($361,802)
0.00
$0
($1,065,500)
0.00
$0
($1,091,553)
Rapport Therapeutics, Inc.
0.00
$0
($361,021)
0.25
$578,474
($2,351,082)
0.28
$740,711
($2,605,859)
Cormedix Inc.
0.00
$0
($342,600)
0.80
$275,500
($342,600)
0.80
$275,500
($342,600)
Sagimet Biosciences Inc.
0.00
$0
($289,979)
0.00
$0
($1,062,172)
0.00
$0
($1,062,172)
Zai Lab Ltd
0.00
$0
($283,408)
0.28
$289,100
($1,020,458)
0.09
$289,100
($3,201,350)
Regeneron Pharmaceuticals, Inc.
0.00
$0
($280,766)
0.00
$0
($280,766)
0.00
$0
($280,766)
Emergent Biosolutions Inc.
0.00
$0
($273,143)
0.00
$0
($709,906)
0.34
$349,800
($1,020,674)
Ptc Therapeutics, Inc.
0.00
$0
($271,052)
0.00
$0
($1,034,729)
0.00
$0
($4,553,258)
Urogen Pharma Ltd.
0.00
$0
($250,000)
0.00
$0
($426,900)
0.00
$0
($426,900)
Xeris Biopharma Holdings, Inc.
0.00
$0
($240,076)
0.08
$109,475
($1,455,372)
0.07
$109,475
($1,672,616)
Prestige Consumer Healthcare Inc.
0.00
$0
($238,050)
0.00
$0
($238,050)
0.00
$0
($389,070)
Protagonist Therapeutics, Inc
0.00
$0
($229,896)
0.00
$0
($4,174,474)
0.00
$0
($4,676,856)
Nektar Therapeutics
0.00
$0
($216,794)
0.00
$0
($1,155,577)
0.00
$0
($1,455,064)
Verastem, Inc.
0.00
$0
($208,500)
0.00
$0
($456,608)
0.00
$0
($1,096,803)
Abbott Laboratories
0.00
$0
($203,043)
0.00
$0
($949,801)
0.00
$0
($1,836,142)
Fulcrum Therapeutics, Inc.
0.00
$0
($165,495)
0.00
$0
($165,495)
0.00
$0
($168,015)
Tg Therapeutics, Inc.
0.00
$0
($162,850)
0.00
$0
($1,204,518)
0.00
$0
($1,833,901)
Arcus Biosciences, Inc.
0.00
$0
($125,000)
0.00
$0
($280,561)
1.20
$402,665
($334,471)
Harmony Biosciences Holdings, Inc.
0.00
$0
($119,945)
0.00
$0
($907,323)
0.00
$0
($1,134,709)
Alkermes Plc.
0.00
$0
($117,200)
0.00
$0
($327,343)
0.00
$0
($1,059,355)
Wave Life Sciences Ltd.
0.00
$0
($109,421)
0.00
$0
($2,750,415)
0.00
$0
($2,750,415)
Vera Therapeutics, Inc.
0.00
$0
($107,498)
0.00
$0
($107,498)
0.00
$0
($654,412)
Apellis Pharmaceuticals, Inc.
0.00
$0
($100,300)
0.00
$0
($698,658)
0.00
$0
($3,783,615)
Puma Biotechnology, Inc.
0.00
$0
($97,228)
0.00
$0
($727,675)
0.00
$0
($923,516)
Spero Therapeutics, Inc.
0.00
$0
($95,440)
0.00
$0
($111,726)
0.00
$0
($347,113)
Mannkind Corp
0.00
$0
($94,448)
0.00
$0
($928,130)
0.00
$0
($1,518,088)
Amylyx Pharmaceuticals, Inc.
0.00
$0
($94,418)
0.00
$0
($1,659,825)
0.02
$37,005
($2,124,288)
Ligand Pharmaceuticals Inc
0.00
$0
($91,457)
0.00
$0
($2,340,988)
0.35
$1,156,546
($3,264,987)
Entrada Therapeutics, Inc.
0.00
$0
($88,932)
0.00
$0
($88,932)
0.00
$0
($107,967)
Abeona Therapeutics Inc.
0.00
$0
($71,168)
0.00
$0
($2,000,774)
0.00
$0
($2,220,394)
Septerna, Inc.
0.00
$0
($63,223)
0.00
$0
($63,223)
11.15
$705,165
($63,223)
GENELUX CORP
0.00
$0
($50,008)
0.00
$0
($50,008)
0.00
$0
($195,850)
Rocket Pharmaceuticals, Inc.
0.00
$0
($34,463)
0.13
$34,100
($260,439)
0.18
$135,700
($767,802)
Ironwood Pharmaceuticals Inc
0.00
$0
($19,973)
0.00
$0
($31,045)
0.00
$0
($468,609)
Lyell Immunopharma, Inc.
0.00
$0
($14,247)
0.00
$0
($147,804)
0.85
$126,148
($147,804)
Mural Oncology plc
0.00
$0
($10,475)
0.00
$0
($67,620)
0.00
$0
($160,463)
Enanta Pharmaceuticals Inc
0.00
$0
($8,195)
0.00
$0
($8,195)
1.89
$256,050
($135,188)
Equillium, Inc.
0.00
$0
($7,696)
0.00
$0
($7,696)
0.00
$0
($7,696)
Lifevantage Corp
0.00
$0
($7,330)
0.18
$9,756
($54,520)
0.05
$20,750
($419,140)
Assertio Holdings, Inc.
0.00
$0
($6,806)
0.00
$0
($6,806)
0.00
$0
($6,806)
Rockwell Medical, Inc.
0.00
$0
($4,419)
0.00
$0
($29,298)
0.00
$0
($47,348)
Xenon Pharmaceuticals Inc.
0.00
$0
($4,366)
0.00
$0
($4,457)
0.00
$0
($4,457)
An2 Therapeutics, Inc.
0.00
$0
($4,086)
0.00
$0
($4,086)
0.75
$20,798
($27,695)
Arvinas, Inc.
0.00
$0
($2,275)
3.49
$227,010
($64,998)
0.25
$227,010
($904,576)
Galera Therapeutics, Inc.
0.00
$0
($1,407)
0.00
$0
($1,407)
355.35
$499,979
($1,407)
Aditxt, Inc.
0.00
$0
($3)
0.00
$0
($3)
0.00
$0
($3)
Catalyst Pharmaceuticals, Inc.
-0.00
$0
$908,000
0.00
$0
($4,412,987)
0.00
$0
($3,369,170)
Verrica Pharmaceuticals Inc.
--
$6,302,590
$0
--
$6,302,590
$0
2247.11
$6,302,590
($2,805)
Biohaven Ltd.
--
$3,000,000
$0
--
$3,000,000
$0
--
$3,000,000
$0
Relmada Therapeutics, Inc.
--
$2,196,700
$0
--
$2,374,795
$0
--
$2,836,106
$0
CervoMed Inc.
--
$529,283
$0
--
$529,283
$0
--
$565,094
$0
Annovis Bio, Inc.
--
$421,322
$0
--
$2,621,323
$0
--
$2,621,323
$0
Johnson & Johnson
--
$257,688
$0
0.08
$257,688
($3,129,830)
0.13
$404,908
($3,129,830)
Edgewise Therapeutics, Inc.
--
$199,403
$0
--
$199,403
$0
--
$199,403
$0
NEONC TECHNOLOGIES HOLDINGS, INC.
--
$192,019
$0
--
$192,019
$0
--
$399,908
$0
Abcellera Biologics Inc.
--
$178,460
$0
--
$178,460
$0
--
$376,528
$0
Nuvectis Pharma, Inc.
--
$168,110
$0
--
$168,110
$0
--
$189,035
$0
Maia Biotechnology, Inc.
--
$153,171
$0
--
$153,171
$0
--
$443,168
$0
Pasithea Therapeutics Corp.
--
$149,999
$0
--
$149,999
$0
189.39
$149,999
($792)
Greenwich Lifesciences, Inc.
--
$127,860
$0
--
$149,158
$0
--
$515,477
$0
BIOXYTRAN, INC
--
$126,000
$0
--
$126,000
$0
--
$126,000
$0
Turn Therapeutics Inc.
--
$108,997
$0
--
$233,995
$0
--
$233,995
$0
Sellas Life Sciences Group, Inc.
--
$100,806
$0
--
$115,606
$0
--
$185,406
$0
Biomea Fusion, Inc.
--
$54,552
$0
--
$54,552
$0
--
$54,552
$0
Tenax Therapeutics, Inc.
--
$49,619
$0
--
$49,619
$0
--
$49,619
$0
Zomedica Corp.
--
$47,026
$0
--
$128,768
$0
--
$344,926
$0
Fibrogen Inc
--
$33,750
$0
--
$33,750
$0
--
$84,413
$0
Cassava Sciences Inc
--
$24,940
$0
--
$64,880
$0
--
$64,880
$0
Lite Strategy, Inc.
--
$22,777
$0
--
$22,777
$0
--
$22,777
$0
Perspective Therapeutics, Inc.
--
$22,295
$0
--
$22,295
$0
--
$308,908
$0
Aptevo Therapeutics Inc.
--
$20,134
$0
--
$20,134
$0
--
$20,134
$0
Annexon, Inc.
--
$18,394
$0
9.10
$72,712
($7,987)
0.54
$72,712
($134,425)
Renovorx, Inc.
--
$17,600
$0
--
$56,296
$0
--
$175,686
$0
Salarius Pharmaceuticals, Inc.
--
$16,000
$0
--
$16,000
$0
--
$16,000
$0
Phio Pharmaceuticals Corp.
--
$12,050
$0
--
$27,065
$0
--
$39,061
$0
Silo Pharma, Inc.
--
$5,582
$0
--
$5,582
$0
--
$12,008
$0
Iterum Therapeutics Plc
--
$2,191
$0
--
$13,045
$0
--
$13,045
$0
Amphastar Pharmaceuticals, Inc.
--
$0
$0
0.00
$0
($63,877)
0.00
$0
($130,930)
Aurinia Pharmaceuticals Inc.
--
$0
$0
0.00
$0
($210,000)
0.00
$0
($6,156,646)
Nurix Therapeutics, Inc.
--
$0
$0
0.00
$0
($138,529)
0.00
$0
($293,159)
Precigen, Inc.
--
$0
$0
0.39
$235,938
($604,192)
0.39
$235,938
($604,192)
Akebia Therapeutics, Inc.
--
$0
$0
0.00
$0
($198,691)
0.00
$0
($885,909)
KALA BIO, Inc.
--
$0
$0
0.00
$0
($371,744)
0.00
$0
($524,771)
Kezar Life Sciences, Inc.
--
$0
$0
0.00
$0
($3,531)
0.00
$0
($3,531)
Arcturus Therapeutics Holdings Inc.
--
$0
$0
--
$20,499
$0
--
$20,499
$0
Crinetics Pharmaceuticals, Inc.
--
$0
$0
0.00
$0
($189,437)
0.00
$0
($1,310,792)
Travere Therapeutics, Inc.
--
$0
$0
0.00
$0
($306,229)
0.00
$0
($2,755,998)
United Therapeutics Corp
--
$0
$0
0.00
$0
($1,215,016)
0.00
$0
($1,305,736)
Anixa Biosciences Inc
--
$0
$0
--
$139,200
$0
--
$325,241
$0
Cumberland Pharmaceuticals Inc
--
$0
$0
--
$21,248
$0
--
$51,956
$0
Akero Therapeutics, Inc.
--
$0
$0
0.00
$0
($6,641,266)
0.00
$0
($17,222,233)
Olema Pharmaceuticals, Inc.
--
$0
$0
0.00
$0
($163,700)
0.00
$0
($2,100,096)
Q32 Bio Inc.
--
$0
$0
0.00
$0
($31,921)
0.00
$0
($31,921)
Hookipa Pharma Inc.
--
$0
$0
0.00
$0
($60,046)
0.00
$0
($60,046)
Galectin Therapeutics Inc
--
$0
$0
--
$17,420
$0
--
$52,303
$0
Tharimmune, Inc.
--
$0
$0
--
$592,423
$0
--
$603,176
$0
Bausch Health Companies Inc.
--
$0
$0
0.00
$0
($219,621)
0.00
$0
($219,621)
Soleno Therapeutics Inc
--
$0
$0
0.00
$0
($316,971)
0.00
$0
($2,269,296)
Uniqure N.V.
--
$0
$0
0.00
$0
($322,426)
0.00
$0
($1,396,278)
89Bio, Inc.
--
$0
$0
0.00
$0
($115,280)
0.79
$219,300
($277,638)
Ultragenyx Pharmaceutical Inc.
--
$0
$0
0.00
$0
($421,046)
0.00
$0
($6,197,465)
Bolt Biotherapeutics, Inc.
--
$0
$0
--
$1,373
$0
--
$3,856
$0
Verona Pharma Plc
--
$0
$0
0.00
$0
($9,120,880)
0.00
$0
($27,039,927)
Syndax Pharmaceuticals Inc
--
$0
$0
0.00
$0
($81,987)
0.58
$241,896
($418,160)
Abbvie Inc.
--
$0
$0
0.00
$0
($2,639,219)
0.00
$0
($32,264,257)
Karyopharm Therapeutics Inc.
--
$0
$0
0.00
$0
($21,174)
0.00
$0
($200,116)
Alnylam Pharmaceuticals, Inc.
--
$0
$0
0.00
$0
($18,508,993)
0.00
$0
($23,611,223)
Agios Pharmaceuticals, Inc.
--
$0
$0
0.00
$0
($315,091)
0.00
$0
($315,091)
Phathom Pharmaceuticals, Inc.
--
$0
$0
0.00
$0
($26,804)
0.88
$249,516
($284,028)
Bristol Myers Squibb Co
--
$0
$0
0.00
$0
($2,650,480)
0.16
$412,284
($2,650,480)
Vanda Pharmaceuticals Inc.
--
$0
$0
1.29
$41,500
($32,130)
15.99
$513,636
($32,130)
Dyne Therapeutics, Inc.
--
$0
$0
5.00
$911,000
($182,105)
1.86
$911,000
($488,838)
Dynavax Technologies Corp
--
$0
$0
--
$41,116
$0
0.06
$41,116
($661,866)
Blueprint Medicines Corp
--
$0
$0
0.00
$0
($285,100)
0.00
$0
($8,805,564)
Xencor Inc
--
$0
$0
0.00
$0
($132,464)
0.00
$0
($726,467)
Perrigo Co Plc
--
$0
$0
--
$355,653
$0
0.91
$450,503
($497,495)
Roivant Sciences Ltd.
--
$0
$0
--
$49,957
$0
--
$49,957
$0
Evolus, Inc.
--
$0
$0
0.30
$393,486
($1,326,167)
0.10
$393,486
($3,900,468)
Kalvista Pharmaceuticals, Inc.
--
$0
$0
0.00
$0
($992,221)
0.00
$0
($992,221)
Cryoport, Inc.
--
$0
$0
0.00
$0
($158,021)
0.00
$0
($331,589)
Immuneering Corp
--
$0
$0
--
$475,826
$0
--
$475,826
$0
Viatris Inc
--
$0
$0
3.05
$219,740
($72,045)
10.49
$756,002
($72,045)
Gossamer Bio, Inc.
--
$0
$0
--
$50,016
$0
--
$50,016
$0
Esperion Therapeutics, Inc.
--
$0
$0
0.00
$0
($170,891)
0.00
$0
($244,239)
XOMA Royalty Corp
--
$0
$0
--
$50,780
$0
--
$756,645
$0
Oric Pharmaceuticals, Inc.
--
$0
$0
0.08
$262,899
($3,482,406)
0.08
$262,899
($3,482,406)
Tonix Pharmaceuticals Holding Corp.
--
$0
$0
--
$24,061
$0
--
$110,261
$0
Igm Biosciences, Inc.
--
$0
$0
0.00
$0
($40,568)
0.00
$0
($107,771)
Alzamend Neuro, Inc.
--
$0
$0
0.00
$0
($69)
104.31
$13,225
($127)
CalciMedica, Inc.
--
$0
$0
--
$60,198
$0
--
$74,608
$0
Synlogic, Inc.
--
$0
$0
0.00
$0
($284)
0.00
$0
($3,259)
Nuvation Bio Inc.
--
$0
$0
--
$1,103,906
$0
--
$1,924,126
$0
Disc Medicine, Inc.
--
$0
$0
0.00
$0
($489,148)
0.00
$0
($1,815,896)
Schrodinger, Inc.
--
$0
$0
0.00
$0
($29,387)
0.00
$0
($260,045)
Bespoke Extracts, Inc.
--
$0
$0
--
$2,640
$0
--
$5,410
$0
Bicycle Therapeutics Plc
--
$0
$0
0.00
$0
($170,024)
0.00
$0
($802,917)
Nkarta, Inc.
--
$0
$0
0.00
$0
($3,204)
0.00
$0
($110,751)
Kiniksa Pharmaceuticals International, plc
--
$0
$0
0.00
$0
($124,397)
0.00
$0
($494,872)
Aquestive Therapeutics, Inc.
--
$0
$0
0.00
$0
($907,995)
0.00
$0
($907,995)
Anaptysbio, Inc
--
$0
$0
0.00
$0
($144,539)
0.00
$0
($144,539)
Savara Inc
--
$0
$0
--
$98,572
$0
1.84
$535,647
($290,675)
Immunic, Inc.
--
$0
$0
--
$114,828
$0
--
$246,928
$0
Cellectar Biosciences, Inc.
--
$0
$0
--
$124,750
$0
--
$133,150
$0
Mirum Pharmaceuticals, Inc.
--
$0
$0
0.00
$0
($155,091)
0.00
$0
($1,911,152)
Macrogenics Inc
--
$0
$0
--
$150,515
$0
--
$150,515
$0
Alx Oncology Holdings Inc
--
$0
$0
45.32
$157,755
($3,481)
5.02
$157,755
($31,433)
Avidity Biosciences, Inc.
--
$0
$0
0.00
$0
($1,438,599)
0.00
$0
($6,836,835)
Pmv Pharmaceuticals, Inc.
--
$0
$0
0.00
$0
($152,104)
0.00
$0
($152,104)
Eton Pharmaceuticals, Inc.
--
$0
$0
0.00
$0
($3,544,731)
0.00
$0
($4,770,642)
Supernus Pharmaceuticals, Inc.
--
$0
$0
0.00
$0
($2,605,335)
0.00
$0
($2,605,335)
OnKure Therapeutics, Inc.
--
$0
$0
0.00
$0
($1,958)
0.00
$0
($13,706)
Summit Therapeutics Inc.
--
$0
$0
--
$5,984,756
$0
--
$5,984,756
$0
ZEVRA THERAPEUTICS, INC.
--
$0
$0
1.03
$228,343
($221,004)
0.27
$310,319
($1,140,979)
Soligenix, Inc.
--
$0
$0
--
$20,000
$0
--
$20,000
$0
Kronos Bio, Inc.
--
$0
$0
0.00
$0
($21,554)
0.00
$0
($21,554)
Centessa Pharmaceuticals Plc
--
$0
$0
0.00
$0
($301,597)
0.00
$0
($5,426,895)
Viking Therapeutics, Inc.
--
$0
$0
0.00
$0
($4,916,707)
0.00
$29,943
($17,698,502)
Rezolute, Inc.
--
$0
$0
--
$41,186
$0
--
$256,119
$0
Context Therapeutics Inc.
--
$0
$0
--
$37,006
$0
--
$37,006
$0
Xilio Therapeutics, Inc.
--
$0
$0
--
$72,765
$0
--
$72,765
$0
Axsome Therapeutics, Inc.
--
$0
$0
0.01
$200,466
($13,373,843)
0.01
$200,466
($14,479,691)
Immix Biopharma, Inc.
--
$0
$0
--
$20,241
$0
--
$124,599
$0
Ainos, Inc.
--
$0
$0
0.00
$0
($23,639)
0.00
$0
($23,639)
AYTU BIOPHARMA, INC
--
$0
$0
--
$124,998
$0
--
$144,498
$0
Aldeyra Therapeutics, Inc.
--
$0
$0
0.12
$13,250
($113,713)
0.12
$13,250
($113,713)
Oncotelic Therapeutics, Inc.
--
$0
$0
--
$994
$0
--
$10,705
$0
Geovax Labs, Inc.
--
$0
$0
--
$6,240
$0
--
$40,123
$0
Earth Science Tech, Inc.
--
$0
$0
--
$48,349
$0
--
$295,969
$0
MoonLake Immunotherapeutics
--
$0
$0
--
$98,808
$0
--
$98,808
$0
Terns Pharmaceuticals, Inc.
--
$0
$0
16.89
$186,595
($11,047)
1.32
$297,063
($224,504)
Lexaria Bioscience Corp.
--
$0
$0
--
$23,844
$0
--
$23,844
$0
Rani Therapeutics Holdings, Inc.
--
$0
$0
--
$1,260,417
$0
--
$1,310,385
$0
Aspire Biopharma Holdings, Inc.
--
$0
$0
1.00
$7,800
($7,800)
1.00
$7,800
($7,800)
Carisma Therapeutics Inc.
--
$0
$0
0.00
$0
($124,343)
0.00
$0
($124,343)
ELITE PHARMACEUTICALS INC /NV/
--
$0
$0
0.02
$9,640
($615,000)
0.02
$9,640
($615,000)
Akari Therapeutics Plc
--
$0
$0
--
$56,660
$0
--
$56,660
$0
MetaVia Inc.
--
$0
$0
--
$9,940
$0
--
$9,940
$0
Quoin Pharmaceuticals, Ltd.
--
$0
$0
--
$128,640
$0
--
$728,640
$0
NewAmsterdam Pharma Co N.V.
--
$0
$0
0.00
$0
($659,019)
0.00
$0
($659,019)
Cadrenal Therapeutics, Inc.
--
$0
$0
0.00
$0
($640,578)
0.00
$0
($640,578)
JUPITER NEUROSCIENCES, INC.
--
$0
$0
--
$4,439
$0
--
$4,439
$0
BullFrog AI Holdings, Inc.
--
$0
$0
0.00
$0
($76,536)
0.00
$0
($150,630)
Zenas Biopharma, Inc.
--
$0
$0
--
$249,992
$0
--
$943,442
$0
Camp4 Therapeutics Corp
--
$0
$0
--
$54,996
$0
--
$54,996
$0
Sionna Therapeutics, Inc.
--
$0
$0
0.00
$0
($1,966,634)
0.00
$0
($1,966,634)
Aardvark Therapeutics, Inc.
--
$0
$0
--
$305,717
$0
--
$305,717
$0
Avid Bioservices, Inc.
--
$0
$0
--
$0
$0
0.00
$0
($2,785,375)
Day One Biopharmaceuticals, Inc.
--
$0
$0
--
$0
$0
0.00
$0
($399,339)
Zentalis Pharmaceuticals, Inc.
--
$0
$0
--
$0
$0
3.86
$252,786
($65,472)
Y-Mabs Therapeutics, Inc.
--
$0
$0
--
$0
$0
0.00
$0
($76,905)
Cartesian Therapeutics, Inc.
--
$0
$0
--
$0
$0
4.80
$2,930,893
($610,064)
2Seventy Bio, Inc.
--
$0
$0
--
$0
$0
0.00
$0
($432,992)
Clearside Biomedical, Inc.
--
$0
$0
--
$0
$0
--
$13,800
$0
Biomarin Pharmaceutical Inc
--
$0
$0
--
$0
$0
0.00
$0
($809,527)
LIFECORE BIOMEDICAL, INC. \DE\
--
$0
$0
--
$0
$0
--
$97,580
$0
Repare Therapeutics Inc.
--
$0
$0
--
$0
$0
0.00
$0
($42,488)
Regulus Therapeutics Inc.
--
$0
$0
--
$0
$0
0.55
$170,899
($310,669)
Checkpoint Therapeutics, Inc.
--
$0
$0
--
$0
$0
0.00
$0
($4,598,055)
Chimerix Inc
--
$0
$0
--
$0
$0
0.00
$0
($91,140)
Rhythm Pharmaceuticals, Inc.
--
$0
$0
--
$0
$0
0.00
$0
($1,948,121)
Zoetis Inc.
--
$0
$0
--
$0
$0
0.00
$0
($367,289)
Aprea Therapeutics, Inc.
--
$0
$0
--
$0
$0
--
$10,110
$0
Tvardi Therapeutics, Inc.
--
$0
$0
--
$0
$0
0.00
$0
($5,301)
Altimmune, Inc.
--
$0
$0
--
$0
$0
--
$57,780
$0
Elanco Animal Health Inc
--
$0
$0
--
$0
$0
--
$211,000
$0
Corbus Pharmaceuticals Holdings, Inc.
--
$0
$0
--
$0
$0
0.00
$0
($160,802)
Generation Bio Co.
--
$0
$0
--
$0
$0
--
$203,209
$0
Ibio, Inc.
--
$0
$0
--
$0
$0
--
$154,996
$0
Optinose, Inc.
--
$0
$0
--
$0
$0
0.00
$0
($58,362)
Applied Therapeutics, Inc.
--
$0
$0
--
$0
$0
0.00
$0
($94,797)
Assembly Biosciences, Inc.
--
$0
$0
--
$0
$0
0.00
$0
($14,664)
Oragenics Inc
--
$0
$0
--
$0
$0
0.00
$0
($1,319)
Longeveron Inc.
--
$0
$0
--
$0
$0
0.00
$0
($36,757)
Alaunos Therapeutics, Inc.
--
$0
$0
--
$0
$0
0.00
$0
($6,022)
Cue Biopharma, Inc.
--
$0
$0
--
$0
$0
--
$30,900
$0
Neurogene Inc.
--
$0
$0
--
$0
$0
0.00
$0
($179,250)
Arbutus Biopharma Corp
--
$0
$0
--
$0
$0
0.00
$0
($251,655)
Phibro Animal Health Corp
--
$0
$0
--
$0
$0
--
$110,500
$0
Sarepta Therapeutics, Inc.
--
$0
$0
--
$0
$0
0.00
$0
($205,400)
Veru Inc.
--
$0
$0
--
$0
$0
--
$84,351
$0
MARINUS PHARMACEUTICALS, INC.
--
$0
$0
--
$0
$0
0.00
$0
($1,733)
Vyne Therapeutics Inc.
--
$0
$0
--
$0
$0
--
$43,800
$0
Pliant Therapeutics, Inc.
--
$0
$0
--
$0
$0
0.00
$0
($1,501,298)
Design Therapeutics, Inc.
--
$0
$0
--
$0
$0
0.00
$0
($23,864)
Prelude Therapeutics Inc
--
$0
$0
--
$0
$0
--
$852,007
$0
Cogent Biosciences, Inc.
--
$0
$0
--
$0
$0
--
$332,412
$0
Pfizer Inc
--
$0
$0
--
$0
$0
7.70
$499,072
($64,825)
Therapeuticsmd, Inc.
--
$0
$0
--
$0
$0
--
$2,809
$0
Immunome Inc.
--
$0
$0
--
$0
$0
--
$2,430,579
$0
Janux Therapeutics, Inc.
--
$0
$0
--
$0
$0
0.00
$0
($2,436,594)
Pds Biotechnology Corp
--
$0
$0
--
$0
$0
--
$50,001
$0
Atai Life Sciences N.V.
--
$0
$0
--
$0
$0
0.00
$0
($246,038)
Palatin Technologies Inc
--
$0
$0
--
$0
$0
--
$10,180
$0
Jade Biosciences, Inc.
--
$0
$0
--
$0
$0
--
$44,400
$0
Atossa Therapeutics, Inc.
--
$0
$0
--
$0
$0
--
$16,887
$0
Ovid Therapeutics Inc.
--
$0
$0
--
$0
$0
0.97
$4,971
($5,141)
Hcw Biologics Inc.
--
$0
$0
--
$0
$0
--
$3,045,056
$0
Organon & Co.
--
$0
$0
--
$0
$0
--
$651,626
$0
PALVELLA THERAPEUTICS, INC.
--
$0
$0
--
$0
$0
--
$102,045
$0
Opus Genetics, Inc.
--
$0
$0
--
$0
$0
--
$97,600
$0
Acurx Pharmaceuticals, Inc.
--
$0
$0
--
$0
$0
--
$170,000
$0
Ventyx Biosciences, Inc.
--
$0
$0
--
$0
$0
0.00
$0
($51,860)
Nrx Pharmaceuticals, Inc.
--
$0
$0
--
$0
$0
--
$46,800
$0
Io Biotech, Inc.
--
$0
$0
--
$0
$0
--
$75,761
$0
Atea Pharmaceuticals, Inc.
--
$0
$0
--
$0
$0
0.08
$81,498
($1,023,475)
Geron Corp
--
$0
$0
--
$0
$0
--
$221,880
$0
Unity Biotechnology, Inc.
--
$0
$0
--
$0
$0
0.00
$0
($145,017)
TALPHERA, INC.
--
$0
$0
--
$0
$0
--
$128,199
$0
Avadel Pharmaceuticals Plc
--
$0
$0
--
$0
$0
--
$462,327
$0
Tango Therapeutics, Inc.
--
$0
$0
--
$0
$0
0.00
$0
($143,227)
Maravai Lifesciences Holdings, Inc.
--
$0
$0
--
$0
$0
0.00
$0
($125,750)
Rigel Pharmaceuticals Inc
--
$0
$0
--
$0
$0
0.00
$0
($424,179)
Pepgen Inc.
--
$0
$0
--
$0
$0
14.42
$71,668
($4,971)
Journey Medical Corp
--
$0
$0
--
$0
$0
0.00
$0
($887,229)
AEON Biopharma, Inc.
--
$0
$0
--
$0
$0
--
$84,550
$0
Serina Therapeutics, Inc.
--
$0
$0
--
$0
$0
--
$17,745
$0
Entero Therapeutics, Inc.
--
$0
$0
--
$0
$0
0.00
$0
($465)
60 DEGREES PHARMACEUTICALS, INC.
--
$0
$0
--
$0
$0
--
$125,565
$0
ACELYRIN, Inc.
--
$0
$0
--
$0
$0
0.00
$0
($68,902)
FibroBiologics, Inc.
--
$0
$0
--
$0
$0
--
$16,800
$0
Nika Pharmaceuticals, Inc
--
$0
$0
--
$0
$0
0.00
$0
($500,000)
IMPACT BIOMEDICAL INC.
--
$0
$0
--
$0
$0
--
$1,129
$0
Mbx Biosciences, Inc.
--
$0
$0
--
$0
$0
--
$45,312
$0
Apimeds Pharmaceuticals US, Inc.
--
$0
$0
--
$0
$0
--
$107,074
$0