Industry - Pharmaceutical Preparations

  1. All Sectors
  2. Manufacturing
  3. Chemicals
Latest data: 9/21/2026 10:01:34 PM
1 Month
Buy/Sell Ratio 0.16
13%
87%
Buy Sell
$13.10 M ($82.54) M
33 Insiders 114 Insiders
53 Transactions 145 Transactions
8/21/2026 to 9/21/2026
3 Month
Buy/Sell Ratio 0.10
9%
91%
Buy Sell
$31.52 M ($316.68) M
102 Insiders 305 Insiders
167 Transactions 467 Transactions
6/21/2026 to 9/21/2026
6 Month
Buy/Sell Ratio 0.16
13%
87%
Buy Sell
$93.33 M ($589.10) M
171 Insiders 518 Insiders
325 Transactions 1030 Transactions
3/21/2026 to 9/21/2026
12 Month
Buy/Sell Ratio 0.13
11%
89%
Buy Sell
$138.44 M ($1,105.63) M
312 Insiders 840 Insiders
632 Transactions 2227 Transactions
9/21/2025 to 9/21/2026

Monthly Buy and Sell Value

Monthly Buy/Sell Ratio

Most Insider Buying

12 months
Name Value Transactions
Summit Therapeutics Inc.
$49,987,200 1
Verrica Pharmaceuticals Inc.
$5,835,050 1
CYBIN INC.
$4,715,337 4
Annovis Bio, Inc.
$4,256,876 8
CYBIN INC.
$3,569,045 3
Apollomics Inc.
$3,549,999 1
Corcept Therapeutics Inc
$3,313,809 1
Biohaven Ltd.
$3,000,000 1
Zenas Biopharma, Inc.
$2,662,720 4
XOMA Royalty Corp
$2,505,000 1

Most Insider Selling

12 months
Name Value Transactions
BeOne Medicines Ltd.
($120,892,072) 9
MoonLake Immunotherapeutics
($62,962,500) 1
BELITE BIO, INC
($20,817,715) 4
Teva Pharmaceutical Industries Ltd
($20,725,392) 3
Arrowhead Pharmaceuticals, Inc.
($20,434,989) 6
Vertex Pharmaceuticals Inc / Ma
($19,738,855) 1
Opus Genetics, Inc.
($15,995,000) 2
Mineralys Therapeutics, Inc.
($14,907,009) 7
Insmed Inc
($14,692,249) 1
Viking Therapeutics, Inc.
($14,004,932) 3

Most Unique Insiders Buying (>25K)

12 months
Name Unique insiders Total Trades
Indivior Pharmaceuticals, Inc. 7 8
Elanco Animal Health Inc 6 9
HYPERION DEFI, INC. 5 6
Quoin Pharmaceuticals, Ltd. 5 5
Braveheart Bio, Inc. 5 5
Relmada Therapeutics, Inc. 4 10
CervoMed Inc. 4 9
Maia Biotechnology, Inc. 4 8
Hepion Pharmaceuticals, Inc. 4 6
ONCOLYTICS BIOTECH INC 4 6

Most Unique Insiders Selling (>25K)

12 months
Name Unique insiders Total Trades
TAKEDA PHARMACEUTICAL CO LTD 13 17
Vertex Pharmaceuticals Inc / Ma 12 53
Ani Pharmaceuticals Inc 11 41
Ionis Pharmaceuticals Inc 11 26
Uniqure N.V. 11 17
BeOne Medicines Ltd. 10 34
Arrowhead Pharmaceuticals, Inc. 10 21
Insmed Inc 9 38
Abeona Therapeutics Inc. 9 33
Ultragenyx Pharmaceutical Inc. 9 23

Companies with activity

1 Month 6 Month 12 Month
Name Ratio Buy $ Sell $ Ratio Buy $ Sell $ Ratio Buy $ Sell $
An2 Therapeutics, Inc. 7.71 $11,602 ($1,504) 0.42 $11,602 ($27,481) 0.14 $11,602 ($81,598)
NewAmsterdam Pharma Co N.V. 5.59 $226,500 ($40,512) 5.59 $226,500 ($40,512) 0.07 $226,500 ($3,461,426)
Lifevantage Corp 0.11 $6,071 ($55,649) 0.22 $12,130 ($55,649) 3.11 $195,986 ($62,979)
BELITE BIO, INC 0.00 $0 ($31,886,076) 0.00 $0 ($37,684,720) 0.00 $0 ($37,684,720)
Pharvaris N.V. 0.00 $0 ($7,090,276) 0.00 $0 ($11,898,183) 0.00 $0 ($11,898,183)
Madrigal Pharmaceuticals, Inc. 0.00 $0 ($6,239,198) 0.00 $0 ($10,461,835) 0.00 $0 ($17,158,081)
PALVELLA THERAPEUTICS, INC. 0.00 $0 ($4,167,146) 0.01 $49,974 ($4,167,146) 0.20 $849,974 ($4,167,146)
Rapport Therapeutics, Inc. 0.00 $0 ($3,844,038) 0.00 $0 ($9,564,511) 0.00 $0 ($11,615,846)
Insmed Inc 0.00 $0 ($3,100,000) 0.00 $0 ($12,283,366) 0.00 $0 ($39,141,026)
Amylyx Pharmaceuticals, Inc. 0.00 $0 ($2,944,962) 0.01 $51,338 ($3,483,830) 0.02 $152,183 ($6,868,137)
Jazz Pharmaceuticals Plc 0.00 $0 ($2,275,968) 0.00 $0 ($10,319,789) 0.00 $0 ($19,761,211)
Regeneron Pharmaceuticals, Inc. 0.00 $0 ($2,002,458) 0.00 $0 ($2,280,739) 0.00 $0 ($2,717,908)
Ligand Pharmaceuticals Inc 0.00 $0 ($1,772,434) 0.00 $0 ($4,476,521) 0.00 $0 ($7,062,452)
KAMADA LTD 0.00 $0 ($1,650,459) 0.00 $0 ($1,650,459) 0.00 $0 ($1,650,459)
Precigen, Inc. 0.00 $0 ($1,376,400) 0.01 $24,662 ($4,467,859) 0.02 $92,957 ($5,927,950)
Climb Bio, Inc. 0.00 $0 ($1,366,820) 0.00 $0 ($1,366,820) 0.00 $0 ($2,246,202)
Spyre Therapeutics, Inc. 0.00 $0 ($1,309,410) 0.00 $0 ($14,876,417) 0.00 $0 ($17,946,596)
Biomarin Pharmaceutical Inc 0.00 $0 ($1,163,748) 0.00 $0 ($1,340,430) 0.00 $0 ($4,318,214)
Ani Pharmaceuticals Inc 0.00 $0 ($1,099,025) 0.00 $0 ($7,823,808) 0.00 $0 ($12,456,193)
Evolus, Inc. 0.00 $0 ($950,019) 0.00 $0 ($950,019) 0.00 $0 ($1,121,292)
TAKEDA PHARMACEUTICAL CO LTD 0.00 $0 ($640,279) 0.00 $0 ($10,576,868) 0.00 $0 ($10,576,868)
Cytokinetics Inc 0.00 $0 ($504,190) 0.00 $0 ($7,429,784) 0.00 $0 ($14,879,095)
Oruka Therapeutics, Inc. 0.00 $0 ($471,872) 0.00 $0 ($3,268,113) 0.00 $0 ($3,410,887)
Bristol Myers Squibb Co 0.00 $0 ($437,248) 0.00 $0 ($2,287,264) 0.00 $0 ($2,287,264)
Xenon Pharmaceuticals Inc. 0.00 $0 ($425,829) 0.00 $0 ($1,199,867) 0.00 $0 ($2,346,746)
Roivant Sciences Ltd. 0.00 $0 ($399,382) 0.00 $0 ($16,323,265) 0.00 $0 ($17,523,838)
Aardvark Therapeutics, Inc. 0.00 $0 ($394,957) 0.00 $0 ($394,957) 0.37 $144,595 ($394,957)
Arcutis Biotherapeutics, Inc. 0.00 $0 ($341,839) 0.00 $0 ($1,411,541) 0.00 $0 ($11,398,211)
Ocular Therapeutix, Inc 0.00 $0 ($333,081) 0.00 $0 ($693,500) 0.13 $461,354 ($3,421,542)
Xeris Biopharma Holdings, Inc. 0.00 $0 ($311,242) 0.00 $0 ($2,614,012) 0.00 $0 ($4,409,531)
CRESCENT BIOPHARMA, INC. 0.00 $0 ($285,501) 0.00 $0 ($1,511,627) 0.00 $0 ($1,511,627)
Q32 Bio Inc. 0.00 $0 ($275,144) 0.00 $0 ($275,144) 0.00 $0 ($459,828)
Tg Therapeutics, Inc. 0.00 $0 ($274,800) 0.00 $0 ($274,800) 0.00 $0 ($437,650)
Rocket Pharmaceuticals, Inc. 0.00 $0 ($256,464) 0.00 $0 ($535,661) 0.04 $34,400 ($806,745)
Dyne Therapeutics, Inc. 0.00 $0 ($247,777) 0.23 $190,960 ($816,103) 0.29 $274,840 ($948,858)
Theravance Biopharma, Inc. 0.00 $0 ($226,793) 0.00 $0 ($444,961) 0.00 $0 ($2,860,368)
MapLight Therapeutics, Inc. 0.00 $0 ($192,660) 0.00 $0 ($27,807,711) 0.02 $441,168 ($29,175,788)
Aurinia Pharmaceuticals Inc. 0.00 $0 ($190,427) 0.00 $0 ($546,373) 0.00 $0 ($546,373)
Stoke Therapeutics, Inc. 0.00 $0 ($170,061) 0.00 $0 ($846,619) 0.00 $0 ($7,542,618)
Adlai Nortye Ltd. 0.00 $0 ($164,635) 0.00 $0 ($164,767) 0.00 $0 ($164,767)
BeOne Medicines Ltd. 0.00 $0 ($153,374) 0.00 $0 ($94,547,515) 0.00 $0 ($132,572,056)
GENELUX CORP 0.00 $0 ($146,670) 0.00 $0 ($251,802) 0.00 $0 ($368,042)
Bolt Biotherapeutics, Inc. 0.00 $0 ($128,281) 0.03 $4,442 ($128,281) 0.04 $5,594 ($128,281)
Mannkind Corp 0.00 $0 ($127,856) 0.00 $0 ($352,114) 0.00 $0 ($744,110)
Opus Genetics, Inc. 0.00 $0 ($127,212) 0.00 $0 ($7,810,439) 0.01 $160,275 ($16,591,107)
Aquestive Therapeutics, Inc. 0.00 $0 ($120,487) 0.00 $0 ($467,270) 0.00 $0 ($2,944,580)
Korro Bio, Inc. 0.00 $0 ($99,436) 0.00 $0 ($538,566) 0.00 $0 ($538,566)
Alkermes Plc. 0.00 $0 ($97,652) 0.00 $0 ($994,906) 0.00 $0 ($1,726,021)
Abeona Therapeutics Inc. 0.00 $0 ($87,966) 0.00 $0 ($2,107,694) 0.00 $0 ($3,698,578)
NovaBridge Biosciences 0.00 $0 ($79,904) 4.71 $577,300 ($122,488) 4.71 $577,300 ($122,488)
Amphastar Pharmaceuticals, Inc. 0.00 $0 ($75,306) 0.00 $0 ($237,158) 0.00 $0 ($370,902)
Mirum Pharmaceuticals, Inc. 0.00 $0 ($65,800) 0.00 $0 ($2,061,295) 0.00 $0 ($3,273,974)
Ascendis Pharma A/S 0.00 $0 ($62,335) 0.17 $777,066 ($4,703,356) 0.17 $777,066 ($4,703,356)
Puma Biotechnology, Inc. 0.00 $0 ($45,500) 0.00 $0 ($1,129,758) 0.00 $0 ($1,548,747)
Travere Therapeutics, Inc. 0.00 $0 ($42,610) 0.00 $0 ($4,167,030) 0.00 $0 ($10,050,730)
CYPHERPUNK TECHNOLOGIES INC. 0.00 $0 ($34,400) 0.00 $0 ($77,030) 0.00 $0 ($77,030)
Acrivon Therapeutics, Inc. 0.00 $0 ($30,969) 0.00 $0 ($38,834) 2.94 $114,341 ($38,834)
Corcept Therapeutics Inc 0.00 $0 ($29,843) 0.00 $0 ($530,649) 3.70 $3,313,809 ($894,719)
Upstream Bio, Inc. 0.00 $0 ($27,604) 0.00 $0 ($58,226) 0.00 $0 ($104,796)
Ultragenyx Pharmaceutical Inc. 0.00 $0 ($19,663) 0.00 $0 ($914,719) 0.00 $0 ($3,952,204)
Liquidia Corp 0.00 $0 ($18,566) 0.00 $0 ($2,427,710) 0.00 $0 ($7,226,841)
Generate Biomedicines, Inc. 0.00 $0 ($16,002) 0.00 $0 ($16,002) 16.50 $264,000 ($16,002)
Corbus Pharmaceuticals Holdings, Inc. 0.00 $0 ($15,683) 0.33 $126,255 ($381,156) 0.20 $126,255 ($628,664)
Chemomab Therapeutics Ltd. 0.00 $0 ($6,516) 3.11 $20,246 ($6,516) 3.11 $20,246 ($6,516)
Lyell Immunopharma, Inc. 0.00 $0 ($6,350) 0.00 $0 ($251,600) 0.00 $0 ($604,312)
Imunon, Inc. 0.00 $0 ($3,950) 0.00 $0 ($38,153) 0.00 $0 ($38,153)
Alzamend Neuro, Inc. 0.00 $0 ($3,116) 1.33 $4,135 ($3,116) 0.29 $4,135 ($14,069)
Abbott Laboratories 0.00 $0 ($2,958) 1.70 $1,100,177 ($645,463) 1.64 $2,187,508 ($1,333,826)
Karyopharm Therapeutics Inc. 0.00 $0 ($38) 0.00 $0 ($40,136) 0.00 $0 ($351,588)
NEONC TECHNOLOGIES HOLDINGS, INC. -18.53 $311,416 $16,809 -66.83 $1,123,416 $16,809 -78.26 $1,315,435 $16,809
CYBIN INC. -- $9,631,432 $0 -- $9,631,432 $0 -- $9,631,432 $0
Relmada Therapeutics, Inc. -- $1,671,990 $0 -- $1,671,990 $0 -- $4,030,050 $0
Maia Biotechnology, Inc. -- $336,016 $0 -- $455,893 $0 -- $759,062 $0
Quoin Pharmaceuticals, Ltd. -- $279,966 $0 -- $279,966 $0 -- $408,606 $0
Grace Therapeutics, Inc. -- $214,000 $0 -- $214,000 $0 -- $214,000 $0
Tenax Therapeutics, Inc. -- $132,828 $0 -- $132,828 $0 -- $230,613 $0
Adagene Inc. -- $63,980 $0 -- $156,244 $0 -- $156,244 $0
Indivior Pharmaceuticals, Inc. -- $53,535 $0 0.04 $107,955 ($2,829,211) 0.11 $311,563 ($2,829,211)
Anixa Biosciences Inc -- $49,350 $0 -- $249,135 $0 -- $279,535 $0
Biovie Inc. -- $49,118 $0 -- $49,118 $0 -- $49,118 $0
Telix Pharmaceuticals Ltd -- $19,998 $0 -- $19,998 $0 -- $19,998 $0
Tyra Biosciences, Inc. -- $19,982 $0 -- $19,982 $0 0.00 $19,982 ($4,811,300)
Phio Pharmaceuticals Corp. -- $12,360 $0 -- $49,960 $0 -- $72,260 $0
Veraxa Biotech Holding AG -- $7,650 $0 -- $7,650 $0 -- $7,650 $0
Ctt Pharmaceutical Holdings, Inc. -- $1,611 $0 -- $3,331 $0 -- $15,132 $0
Enliven Therapeutics, Inc. -- $0 $0 0.00 $0 ($1,202,806) 0.00 $0 ($1,498,645)
Bridgebio Pharma, Inc. -- $0 $0 0.00 $0 ($5,891,214) 0.00 $0 ($14,782,718)
Eli Lilly & Co -- $0 $0 0.00 $0 ($12,885,095) 0.00 $0 ($13,895,595)
Arrowhead Pharmaceuticals, Inc. -- $0 $0 0.00 $0 ($3,099,219) 0.00 $0 ($34,468,522)
Arvinas, Inc. -- $0 $0 0.00 $0 ($518,078) 0.35 $495,080 ($1,421,163)
Greenwich Lifesciences, Inc. -- $0 $0 -- $97,003 $0 -- $586,328 $0
Nurix Therapeutics, Inc. -- $0 $0 0.00 $0 ($910,095) 0.00 $0 ($1,352,437)
Processa Pharmaceuticals, Inc. -- $0 $0 -- $208,638 $0 -- $208,638 $0
Akebia Therapeutics, Inc. -- $0 $0 0.00 $0 ($62,181) 0.09 $86,588 ($962,955)
Verastem, Inc. -- $0 $0 0.00 $0 ($116,585) 0.00 $0 ($725,662)
Prothena Corp Public Ltd Co -- $0 $0 0.00 $0 ($135,975) 0.00 $0 ($135,975)
Crinetics Pharmaceuticals, Inc. -- $0 $0 0.00 $0 ($366,143) 0.00 $0 ($2,520,753)
Ptc Therapeutics, Inc. -- $0 $0 0.00 $0 ($5,752,319) 0.00 $0 ($12,573,679)
United Therapeutics Corp -- $0 $0 0.00 $0 ($1,120,087) 0.00 $0 ($1,715,617)
Urogen Pharma Ltd. -- $0 $0 0.00 $0 ($3,904,953) 0.00 $0 ($4,300,127)
Keros Therapeutics, Inc. -- $0 $0 0.28 $53,350 ($191,130) 0.14 $75,770 ($522,950)
Acadia Pharmaceuticals Inc -- $0 $0 0.00 $0 ($412,305) 0.00 $0 ($1,083,288)
Olema Pharmaceuticals, Inc. -- $0 $0 0.00 $0 ($291,162) 0.00 $0 ($5,277,355)
Entrada Therapeutics, Inc. -- $0 $0 0.00 $0 ($431,185) 0.00 $0 ($1,028,158)
Canton Strategic Holdings, Inc. -- $0 $0 0.00 $0 ($343,882) 0.00 $0 ($343,882)
Shattuck Labs, Inc. -- $0 $0 0.61 $250,000 ($408,600) 0.61 $250,000 ($408,600)
Bausch Health Companies Inc. -- $0 $0 0.00 $0 ($391,690) 0.00 $0 ($506,730)
Pacira Biosciences, Inc. -- $0 $0 0.00 $0 ($442,790) 0.00 $0 ($1,277,179)
Zai Lab Ltd -- $0 $0 0.05 $33,071 ($647,925) 0.04 $65,804 ($1,550,156)
Soleno Therapeutics Inc -- $0 $0 0.00 $0 ($429,344) 0.00 $0 ($429,344)
Uniqure N.V. -- $0 $0 0.00 $0 ($966,917) 0.00 $0 ($2,258,860)
Vertex Pharmaceuticals Inc / Ma -- $0 $0 0.00 $0 ($12,495,241) 0.00 $0 ($65,561,533)
Syndax Pharmaceuticals Inc -- $0 $0 0.00 $0 ($152,376) 0.00 $0 ($780,667)
Nuvectis Pharma, Inc. -- $0 $0 -- $250,000 $0 -- $418,110 $0
HYPERION DEFI, INC. -- $0 $0 -- $29,580 $0 -- $523,626 $0
Teva Pharmaceutical Industries Ltd -- $0 $0 0.00 $0 ($17,350,755) 0.00 $0 ($32,282,669)
Alnylam Pharmaceuticals, Inc. -- $0 $0 0.00 $0 ($1,274,343) 0.00 $0 ($33,971,878)
Vera Therapeutics, Inc. -- $0 $0 0.00 $0 ($1,011,051) 0.10 $249,985 ($2,524,590)
Rhythm Pharmaceuticals, Inc. -- $0 $0 0.00 $0 ($912,703) 0.00 $0 ($3,129,837)
Agios Pharmaceuticals, Inc. -- $0 $0 0.00 $0 ($914,400) 0.00 $0 ($1,066,655)
Zoetis Inc. -- $0 $0 -- $653,094 $0 -- $653,094 $0
Nuvalent, Inc. -- $0 $0 0.00 $0 ($261,363) 0.00 $0 ($12,384,907)
Wave Life Sciences Ltd. -- $0 $0 0.00 $0 ($93,002) 0.00 $0 ($947,139)
Nektar Therapeutics -- $0 $0 0.00 $0 ($2,034,537) 0.00 $0 ($2,433,286)
ARS Pharmaceuticals, Inc. -- $0 $0 0.00 $0 ($33,550) 0.00 $0 ($33,550)
Ardelyx, Inc. -- $0 $0 0.00 $0 ($1,027,139) 0.98 $1,946,331 ($1,988,178)
Collegium Pharmaceutical, Inc -- $0 $0 0.00 $0 ($162,542) 0.00 $0 ($4,285,614)
Abcellera Biologics Inc. -- $0 $0 -- $589,604 $0 -- $913,756 $0
Altimmune, Inc. -- $0 $0 -- $154,199 $0 -- $370,038 $0
Ironwood Pharmaceuticals Inc -- $0 $0 0.00 $0 ($658,523) 0.00 $0 ($1,966,995)
Elanco Animal Health Inc -- $0 $0 -- $1,573,008 $0 -- $2,032,419 $0
Xencor Inc -- $0 $0 0.00 $0 ($422,125) 0.00 $0 ($950,090)
Cryoport, Inc. -- $0 $0 0.00 $0 ($6,680,175) 0.00 $0 ($6,901,051)
Ibio, Inc. -- $0 $0 -- $23,055 $0 -- $98,106 $0
Immuneering Corp -- $0 $0 -- $35,993 $0 -- $336,074 $0
Viatris Inc -- $0 $0 0.00 $0 ($1,093,323) 0.00 $0 ($1,093,323)
Johnson & Johnson -- $0 $0 0.00 $0 ($12,515,010) 0.02 $257,688 ($12,839,773)
Arcus Biosciences, Inc. -- $0 $0 0.00 $0 ($264,989) 0.00 $0 ($3,820,490)
Esperion Therapeutics, Inc. -- $0 $0 0.00 $0 ($240,364) 0.00 $0 ($578,862)
Oramed Pharmaceuticals Inc. -- $0 $0 0.00 $0 ($330,744) 0.00 $0 ($330,744)
Tonix Pharmaceuticals Holding Corp. -- $0 $0 -- $144,728 $0 -- $144,728 $0
Assembly Biosciences, Inc. -- $0 $0 0.00 $0 ($14,687) 0.00 $0 ($14,687)
Royalty Pharma Plc -- $0 $0 0.00 $0 ($4,313,539) 0.00 $0 ($5,870,647)
Fulcrum Therapeutics, Inc. -- $0 $0 0.00 $0 ($65,614) 0.00 $0 ($599,654)
Ionis Pharmaceuticals Inc -- $0 $0 0.00 $0 ($2,534,928) 0.00 $0 ($18,611,165)
Disc Medicine, Inc. -- $0 $0 0.00 $0 ($841,283) 0.00 $0 ($5,034,394)
Annexon, Inc. -- $0 $0 -- $95,840 $0 0.66 $205,847 ($313,428)
Lipocine Inc. -- $0 $0 -- $434,600 $0 -- $434,600 $0
Schrodinger, Inc. -- $0 $0 0.00 $0 ($24,406) 0.00 $0 ($346,988)
Avalo Therapeutics, Inc. -- $0 $0 0.00 $0 ($617,656) 0.00 $0 ($617,656)
Bicycle Therapeutics Plc -- $0 $0 0.00 $0 ($130,437) 0.00 $0 ($551,656)
KYNTRA BIO, INC. -- $0 $0 -- $19,852 $0 -- $53,602 $0
Emergent Biosolutions Inc. -- $0 $0 0.00 $0 ($577,200) 0.00 $0 ($1,156,423)
Protagonist Therapeutics, Inc -- $0 $0 0.00 $0 ($184,572) 0.00 $0 ($5,004,968)
Nkarta, Inc. -- $0 $0 0.00 $0 ($4,813) 0.00 $0 ($70,422)
Kiniksa Pharmaceuticals International, plc -- $0 $0 0.00 $0 ($687,927) 0.00 $0 ($1,190,607)
Zomedica Corp. -- $0 $0 -- $136,191 $0 -- $183,217 $0
Neurogene Inc. -- $0 $0 0.00 $0 ($787,444) 0.00 $0 ($1,133,592)
Phibro Animal Health Corp -- $0 $0 -- $317,700 $0 -- $317,700 $0
Anaptysbio, Inc -- $0 $0 0.00 $0 ($2,247,650) 0.00 $0 ($2,440,993)
Hepion Pharmaceuticals, Inc. -- $0 $0 -- $425,000 $0 -- $425,000 $0
Lite Strategy, Inc. -- $0 $0 -- $21,388 $0 -- $141,864 $0
Cellectar Biosciences, Inc. -- $0 $0 -- $49,997 $0 -- $49,997 $0
Prestige Consumer Healthcare Inc. -- $0 $0 0.00 $0 ($120,444) 0.00 $0 ($424,424)
Macrogenics Inc -- $0 $0 0.00 $0 ($129,086) 0.00 $0 ($129,086)
Veru Inc. -- $0 $0 -- $4,842 $0 -- $4,842 $0
Alx Oncology Holdings Inc -- $0 $0 0.00 $0 ($8,274) 0.00 $0 ($42,588)
Amneal Pharmaceuticals, Inc. -- $0 $0 0.00 $0 ($7,667,124) 0.00 $0 ($8,253,124)
Kura Oncology, Inc. -- $0 $0 0.00 $0 ($1,438,392) 0.00 $0 ($2,940,242)
Edgewise Therapeutics, Inc. -- $0 $0 0.00 $0 ($506,735) 0.39 $199,403 ($506,735)
Cytomx Therapeutics, Inc. -- $0 $0 0.00 $0 ($4,953) 0.00 $0 ($1,694,057)
Genprex, Inc. -- $0 $0 0.00 $0 ($10) 0.00 $0 ($10)
Eton Pharmaceuticals, Inc. -- $0 $0 0.00 $0 ($9,913,490) 0.00 $0 ($9,913,490)
OnKure Therapeutics, Inc. -- $0 $0 0.00 $0 ($3,319) 0.00 $0 ($5,499)
Protagenic Therapeutics, Inc.\New -- $0 $0 -- $30,717 $0 -- $30,717 $0
Corvus Pharmaceuticals, Inc. -- $0 $0 -- $250,236 $0 -- $250,236 $0
Pfizer Inc -- $0 $0 21.98 $2,960,110 ($134,661) 21.98 $2,960,110 ($134,661)
Merck & Co., Inc. -- $0 $0 0.00 $0 ($10,046,142) 0.00 $0 ($29,406,103)
Summit Therapeutics Inc. -- $0 $0 -- $50,709,450 $0 -- $50,709,450 $0
ZEVRA THERAPEUTICS, INC. -- $0 $0 0.00 $0 ($495,047) 0.00 $0 ($619,095)
Immunome Inc. -- $0 $0 0.56 $604,102 ($1,087,626) 1.14 $2,101,730 ($1,840,922)
Verrica Pharmaceuticals Inc. -- $0 $0 -- $210,890 $0 -- $6,513,480 $0
Equillium, Inc. -- $0 $0 0.00 $0 ($723,830) 0.00 $0 ($787,440)
Viking Therapeutics, Inc. -- $0 $0 0.00 $0 ($6,267,665) 0.01 $149,912 ($21,690,334)
Janux Therapeutics, Inc. -- $0 $0 0.00 $0 ($85,822) 0.00 $0 ($347,145)
Larimar Therapeutics, Inc. -- $0 $0 -- $166,890 $0 -- $716,890 $0
Hcw Biologics Inc. -- $0 $0 -- $259,996 $0 -- $259,996 $0
Rezolute, Inc. -- $0 $0 -- $28,500 $0 -- $279,934 $0
Organon & Co. -- $0 $0 0.00 $0 ($553,382) 0.00 $0 ($553,382)
Annovis Bio, Inc. -- $0 $0 -- $1,641,759 $0 -- $4,456,876 $0
Xilio Therapeutics, Inc. -- $0 $0 -- $43,950 $0 -- $43,950 $0
Axsome Therapeutics, Inc. -- $0 $0 0.00 $0 ($4,161,126) 0.00 $0 ($8,188,876)
Cns Pharmaceuticals, Inc. -- $0 $0 -- $44,002 $0 -- $44,002 $0
Dermata Therapeutics, Inc. -- $0 $0 0.00 $0 ($13) 97.01 $1,270 ($13)
Atea Pharmaceuticals, Inc. -- $0 $0 -- $25,446 $0 -- $25,446 $0
Spero Therapeutics, Inc. -- $0 $0 0.00 $0 ($63,352) 0.00 $0 ($552,042)
Aldeyra Therapeutics, Inc. -- $0 $0 -- $418,450 $0 -- $523,550 $0
Oncotelic Therapeutics, Inc. -- $0 $0 -- $37,832 $0 -- $37,832 $0
Natures Sunshine Products Inc -- $0 $0 0.00 $0 ($742,411) 0.00 $0 ($2,094,604)
Rein Therapeutics, Inc. -- $0 $0 -- $74,561 $0 -- $74,561 $0
Lantern Pharma Inc. -- $0 $0 -- $200,001 $0 -- $200,001 $0
Milestone Pharmaceuticals Inc. -- $0 $0 0.00 $0 ($82,490) 0.00 $0 ($180,365)
MoonLake Immunotherapeutics -- $0 $0 0.00 $0 ($71,916,302) 0.00 $98,808 ($77,903,465)
Maravai Lifesciences Holdings, Inc. -- $0 $0 0.00 $0 ($254,000) 1.45 $368,544 ($254,000)
Renovorx, Inc. -- $0 $0 -- $19,690 $0 -- $84,427 $0
Ensysce Biosciences, Inc. -- $0 $0 -- $444,169 $0 -- $444,169 $0
Terns Pharmaceuticals, Inc. -- $0 $0 0.00 $0 ($49,693) 0.00 $0 ($101,652)
Rigel Pharmaceuticals Inc -- $0 $0 0.00 $0 ($160,425) 0.00 $0 ($160,425)
Promis Neurosciences Inc. -- $0 $0 -- $30,324 $0 -- $196,549 $0
HARROW, INC. -- $0 $0 -- $468,720 $0 -- $468,720 $0
Whitehawk Therapeutics, Inc. -- $0 $0 0.00 $0 ($2,459,560) 0.00 $0 ($2,459,560)
Rani Therapeutics Holdings, Inc. -- $0 $0 166.18 $50,033 ($301) 4352.50 $1,310,450 ($301)
Pepgen Inc. -- $0 $0 0.00 $0 ($1,739) 0.00 $0 ($59,312)
ASTRAZENECA PLC -- $0 $0 0.00 $3,211 ($2,209,482) 0.00 $3,211 ($2,209,482)
Legend Biotech Corp -- $0 $0 0.00 $0 ($258,204) 0.00 $0 ($258,204)
AC Immune SA -- $0 $0 0.00 $0 ($59,360) 0.00 $0 ($59,360)
ProQR Therapeutics N.V. -- $0 $0 -- $1,342,385 $0 -- $1,342,385 $0
RedHill Biopharma Ltd. -- $0 $0 0.00 $0 ($2,987) 0.00 $0 ($2,987)
ELITE PHARMACEUTICALS INC /NV/ -- $0 $0 -- $8,610 $0 0.02 $8,610 ($499,200)
Serina Therapeutics, Inc. -- $0 $0 -- $76,881 $0 -- $76,881 $0
NeuroSense Therapeutics Ltd. -- $0 $0 -- $400,000 $0 -- $400,000 $0
Valion Bio, Inc. -- $0 $0 -- $28,408 $0 -- $28,408 $0
NewcelX Ltd. -- $0 $0 -- $374,998 $0 -- $374,998 $0
SciSparc Ltd. -- $0 $0 0.00 $0 ($4,620) 0.00 $0 ($4,620)
Cadrenal Therapeutics, Inc. -- $0 $0 0.00 $0 ($388,290) 0.00 $0 ($999,753)
Mineralys Therapeutics, Inc. -- $0 $0 0.00 $0 ($4,644,544) 0.00 $0 ($16,150,698)
CytoMed Therapeutics Ltd -- $0 $0 -- $428,778 $0 -- $428,778 $0
Apollomics Inc. -- $0 $0 -- $3,950,004 $0 -- $3,950,004 $0
60 DEGREES PHARMACEUTICALS, INC. -- $0 $0 -- $10,131 $0 -- $30,095 $0
Sagimet Biosciences Inc. -- $0 $0 0.00 $0 ($719,429) 0.00 $0 ($1,114,872)
Contineum Therapeutics, Inc. -- $0 $0 0.00 $0 ($165,570) 0.00 $0 ($385,013)
ALUMIS INC. -- $0 $0 0.00 $0 ($394,311) 0.00 $0 ($394,311)
IMPACT BIOMEDICAL INC. -- $0 $0 0.00 $0 ($57,835) 0.00 $0 ($57,835)
Mbx Biosciences, Inc. -- $0 $0 0.00 $0 ($49,089) 0.00 $0 ($49,089)
Camp4 Therapeutics Corp -- $0 $0 7.19 $59,451 ($8,273) 7.19 $59,451 ($8,273)
Nasus Pharma Ltd -- $0 $0 -- $61,809 $0 -- $61,809 $0
Evommune, Inc. -- $0 $0 0.02 $13,260 ($673,747) 0.02 $13,260 ($673,747)
Apnimed, Inc. -- $0 $0 -- $200,000 $0 -- $200,000 $0
Braveheart Bio, Inc. -- $0 $0 -- $4,594,950 $0 -- $4,594,950 $0
Blossomhill Therapeutics, Inc. -- $0 $0 -- $107,200 $0 -- $107,200 $0
Amicus Therapeutics, Inc. -- $0 $0 -- $0 $0 0.00 $0 ($1,471,085)
Apellis Pharmaceuticals, Inc. -- $0 $0 -- $0 $0 0.00 $0 ($2,911,704)
KALA BIO, Inc. -- $0 $0 -- $0 $0 0.00 $0 ($248,725)
Zentalis Pharmaceuticals, Inc. -- $0 $0 -- $0 $0 0.00 $0 ($134,670)
Harmony Biosciences Holdings, Inc. -- $0 $0 -- $0 $0 0.00 $0 ($1,011,950)
Cartesian Therapeutics, Inc. -- $0 $0 -- $0 $0 0.80 $205,797 ($258,671)
Rallybio Corp -- $0 $0 -- $0 $0 0.00 $0 ($3,992)
Galectin Therapeutics Inc -- $0 $0 -- $0 $0 -- $25,546 $0
Enanta Pharmaceuticals Inc -- $0 $0 -- $0 $0 0.00 $0 ($183,167)
Biomea Fusion, Inc. -- $0 $0 -- $0 $0 -- $196,731 $0
Clene Inc. -- $0 $0 -- $0 $0 -- $216,664 $0
Viridian Therapeutics, Inc.\De -- $0 $0 -- $0 $0 0.00 $0 ($70,796)
Abbvie Inc. -- $0 $0 -- $0 $0 0.00 $0 ($5,597,068)
Phathom Pharmaceuticals, Inc. -- $0 $0 -- $0 $0 0.00 $0 ($7,079)
Aprea Therapeutics, Inc. -- $0 $0 -- $0 $0 -- $60,907 $0
Vanda Pharmaceuticals Inc. -- $0 $0 -- $0 $0 0.00 $0 ($2,824,768)
Decoy Therapeutics Inc. -- $0 $0 -- $0 $0 2084.31 $16,000 ($8)
Edesa Biotech, Inc. -- $0 $0 -- $0 $0 -- $46,218 $0
Organogenesis Holdings Inc. -- $0 $0 -- $0 $0 0.02 $40,093 ($2,619,180)
Iterum Therapeutics Plc -- $0 $0 -- $0 $0 -- $2,191 $0
Cingulate Inc. -- $0 $0 -- $0 $0 -- $34,322 $0
Applied Therapeutics, Inc. -- $0 $0 -- $0 $0 0.00 $0 ($4,816)
XOMA Royalty Corp -- $0 $0 -- $0 $0 -- $2,505,000 $0
Oric Pharmaceuticals, Inc. -- $0 $0 -- $0 $0 0.00 $0 ($2,907,028)
Oragenics Inc -- $0 $0 -- $0 $0 0.00 $0 ($198)
Synlogic, Inc. -- $0 $0 -- $0 $0 0.00 $0 ($284)
Assertio Holdings, Inc. -- $0 $0 -- $0 $0 0.00 $0 ($6,806)
Cue Biopharma, Inc. -- $0 $0 -- $0 $0 -- $99,747 $0
Ideaya Biosciences, Inc. -- $0 $0 -- $0 $0 -- $1,647,890 $0
Monopar Therapeutics -- $0 $0 -- $0 $0 0.31 $104,925 ($343,889)
Galera Therapeutics, Inc. -- $0 $0 -- $0 $0 0.00 $0 ($1,407)
Savara Inc -- $0 $0 -- $0 $0 0.00 $0 ($121,220)
Sarepta Therapeutics, Inc. -- $0 $0 -- $0 $0 0.00 $0 ($417,410)
Mustang Bio, Inc. -- $0 $0 -- $0 $0 0.98 $238 ($241)
Lexicon Pharmaceuticals, Inc. -- $0 $0 -- $0 $0 -- $722,624 $0
Avidity Biosciences, Inc. -- $0 $0 -- $0 $0 0.00 $0 ($4,226,448)
Pliant Therapeutics, Inc. -- $0 $0 -- $0 $0 0.00 $0 ($163,620)
Supernus Pharmaceuticals, Inc. -- $0 $0 -- $0 $0 0.00 $0 ($1,540,959)
Cogent Biosciences, Inc. -- $0 $0 -- $0 $0 0.00 $0 ($12,178,705)
Therapeuticsmd, Inc. -- $0 $0 -- $0 $0 -- $14,031 $0
CervoMed Inc. -- $0 $0 -- $0 $0 -- $529,283 $0
Silo Pharma, Inc. -- $0 $0 -- $0 $0 -- $7,657 $0
Soligenix, Inc. -- $0 $0 -- $0 $0 -- $20,000 $0
Cormedix Inc. -- $0 $0 -- $0 $0 0.31 $275,500 ($886,600)
Aditxt, Inc. -- $0 $0 -- $0 $0 0.00 $0 ($5)
Opko Health, Inc. -- $0 $0 -- $0 $0 -- $11,350 $0
Centessa Pharmaceuticals Plc -- $0 $0 -- $0 $0 0.00 $0 ($3,220,338)
Palatin Technologies Inc -- $0 $0 -- $0 $0 0.00 $0 ($9,461)
Ovid Therapeutics Inc. -- $0 $0 -- $0 $0 0.00 $0 ($29,286)
Catalyst Pharmaceuticals, Inc. -- $0 $0 -- $0 $0 -0.00 $0 $908,000
Sellas Life Sciences Group, Inc. -- $0 $0 -- $0 $0 -- $100,806 $0
Immix Biopharma, Inc. -- $0 $0 -- $0 $0 -- $4,976 $0
Rockwell Medical, Inc. -- $0 $0 -- $0 $0 0.00 $0 ($23,677)
TALPHERA, INC. -- $0 $0 -- $0 $0 -- $304,001 $0
Tango Therapeutics, Inc. -- $0 $0 -- $0 $0 0.00 $0 ($1,725,098)
FILANA THERAPEUTICS, INC. -- $0 $0 -- $0 $0 -- $64,880 $0
Geovax Labs, Inc. -- $0 $0 -- $0 $0 -- $5,498 $0
Perspective Therapeutics, Inc. -- $0 $0 -- $0 $0 -- $22,295 $0
Aptevo Therapeutics Inc. -- $0 $0 -- $0 $0 -- $20,134 $0
Pasithea Therapeutics Corp. -- $0 $0 -- $0 $0 -- $149,999 $0
Biohaven Ltd. -- $0 $0 -- $0 $0 -- $3,000,000 $0
Carisma Therapeutics Inc. -- $0 $0 -- $0 $0 0.00 $0 ($124,343)
ONCOLYTICS BIOTECH INC -- $0 $0 -- $0 $0 -- $362,615 $0
BIOXYTRAN, INC -- $0 $0 -- $0 $0 -- $126,000 $0
Mural Oncology plc -- $0 $0 -- $0 $0 0.00 $0 ($25,414)
FibroBiologics, Inc. -- $0 $0 -- $0 $0 -- $120,560 $0
Zenas Biopharma, Inc. -- $0 $0 -- $0 $0 -- $3,412,457 $0
Bicara Therapeutics Inc. -- $0 $0 -- $0 $0 0.00 $0 ($71,981)
Bioage Labs, Inc. -- $0 $0 -- $0 $0 0.00 $0 ($4,223,036)
Septerna, Inc. -- $0 $0 -- $0 $0 0.00 $0 ($63,223)
Turn Therapeutics Inc. -- $0 $0 -- $0 $0 -- $242,745 $0
Ataibeckley Inc. -- $0 $0 -- $0 $0 0.00 $0 ($154,377)
Polaryx Therapeutics, Inc. -- $0 $0 -- $0 $0 -- $7,991 $0